Background: Inflammation and dyslipidemia play an important role in the formation of atherosclerotic plaques in stable coronary artery disease (SCAD). The stenosis degree indicates a visual evaluation of the percentage reduction of coronary diameter compare to normal coronary. This study aims to determine the correlation of lipid profiles, CRP with the stenosis degree in SCAD. Methods: Cross sectional study was carried in 31 patients with SCAD who had coronary angiography at Dr. Kariadi. The study used secondary data from February-March 2018 at Dr. Kariadi Semarang. Secondary data included levels of total cholesterol, LDL, HDL, triglycerides and CRP. The stenosis degree was obtained from coronary angiography in percentage units. Statistical analysis used Latar Belakang: Inflamasi dan dislipidemia berperan penting dalam pembentukan plak aterosklerotik pada penyakit jantung koroner (PJK) stabil. Derajat stenosis menunjukkan evaluasi visual dari persentase pengurangan diameter relatif terhadap segmen normal yang berdekatan. Penelitian ini bertujuan untuk menganalisis hubungan profil lipid dan C-Reactive Protein (CRP) dengan derajat stenosis koroner pada penyakit jantung koroner stabil. Metode: Penelitian potong lintang pada 31 penderita PJK stabil yang telah dilakukan angiografi koroner di RSUP Dr. Kariadi. Penelitian menggunakan data sekunder dari bulan Februari-Maret 2018 di RSUP Dr. Kariadi Semarang. Data sekunder meliputi kadar kolesterol total, LDL, HDL, trigliserida dan CRP. Derajat stenosis koroner diukur berdasarkan angiografi koroner dalam Spearman Correlation test, p < 0,05 was considered significant. Result: Median (min-max) levels of total cholesterol, HDL, LDL, triglycerides, CRP and stenosis degrees respectively are 156 (104-283), 41 (13-67), 102 (60-190), 116 (60-216), 1.50 (0.50-6.54), 70 (20-100). Correlation of total cholesterol, HDL, LDL, triglycerides and CRP levels with a degree of coronary stenosis are (r = 0.123; p = 0.511), (r =-0.132; p = 0.479), (r = 0.073; p = 0.697), (r = 0.117; p = 0.531), (r = 0.026; p = 0.891). Conclusion: There are no significant correlation between lipid profiles, CRP with stenosis degree in SCAD. The effect of statin drugs has an effect on dyslipidemia and as an anti-inflammatory. satuan persentase. Uji statistik menggunakan korelasi Spearman, p < 0,05 dianggap bermakna. Hasil: Median (min-maks) kadar kolesterol total, HDL, LDL, trigliserida, CRP dan derajat stenosis secara berturut-turut yaitu 156 (104-283), 41 (13-67),
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.