Objective: The aim of the study was to find out the etiology of obstructive jaundice and its correlation with the ethnic population of Sikkim. Material and Method: The data of patients with obstructive jaundice admitted under the Department of Gastroenterology was collected retrospectively from March 2019 till February 2020. There were a total of 73 patients of obstructive jaundice patients, the benign etiology was found to be more common than malignant etiology. Results: The male-to-female ratio in our study was 0.35:1. The most common etiology of benign cause of obstructive jaundice was choledocholithiasis (95.83%) followed by common bile duct stricture (3.07%), Mirizzi syndrome (1.53%). The most common causes of malignant obstructive jaundice were carcinoma of gall bladder (62.5%) followed by carcinoma of periampullary region (12.5%), cholangiocarcinoma (12.5%), carcinoma of head of pancreas (12.5%). Conclusions: The most common etiology of obstructive jaundice in this study was choledocholithiasis. There was no any correlation of obstructive jaundice with ethnic population of Sikkim.
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