No abstract

The metabolic syndrome and an increased waist-to-hip ratio are independently associated with a decreased International Index of Erectile Function-5 score. The metabolic syndrome in men older than 50 years is significantly associated with a higher proportion of moderate to severe erectile dysfunction.

Objective. The aim of this study was to evaluate the association between serum levels of testosterone and free testosterone to lifestyle in aging males. Methods. Men between 45 and 85 years were assessed regarding body mass index (BMI), nicotine and alcohol consumption, stress level, physical and social activity, and sleeping quality by a self-administered questionnaire. In parallel, serum levels of testosterone (T), free testosterone (fT), LH, FSH, DHEA-S, E2 and SHBG were obtained. Results. In total, 375 men with a mean age of 59.9 years (9.2 + SD) entered this study; 25.4% and 27.4% had hypogonadal testosterone or free testosterone serum levels, respectively. Nicotine consumption (smokers had higher levels of T and f T; p 5 0.01), BMI (negative correlation to T; p 5 0.01) and age (negative correlation to f T; p 5 0.001) correlated with serum levels of testosterone or free testosterone. Physical and social activity, nicotine and alcohol consumption, stress level and sleep quality did not show a significant association with serum androgen levels.Conclusion. This prospective study of 375 men aged 45 to 85 years confirms the correlation between age, BMI and smoking with serum levels of testosterone and free testosterone, whereas the investigated variety of lifestyle factors did not show a significant association to serum androgen levels.

This study provides the first estimate of the prevalence of ED in different life decades of men in Vienna, and identifies a number of risk factors for this highly prevalent disorder in ageing men.

The increasing length of survival of organ transplant recipients necessitates careful attention to the potential neoplastic complications of life-long immunosuppressive therapy. Due to the rarity of prostate cancer after liver transplantation there are no guidelines for its management. In our case, prostate biopsy revealed prostate cancer in a 59-year-old man after an uncomplicated 5-year post-transplant course. After meticulous lymph node dissection, we performed radical retropubic prostatectomy. The postoperative period was uneventful and the prostate-specific antigen value 18 months after surgery was <0.1 ng/ml. We believe that radical retropubic prostatectomy is technically feasible in patients after liver transplantation and should be offered as a treatment option for every patient with good graft function.