The aim of endodontic therapy is to use various antimicrobial medications for proper cleaning and shaping to create an environment free of microorganisms by eradicating as many as possible from the root canal space. Even although it is a gold standard irrigant, sodium hypochlorite (NaOCl) is known for its cytotoxic effects on vital periapical tissues, making its higher concentrations inappropriate for use in conditions such as wide, underdeveloped, or damaged apices and in cases of perforations. Consequently, if it is ascertained that a gel form of sodium hypochlorite has equivalent antibacterial activity to the aqueous solution form, it could be employed in such situations. The aim of this study was the microbiologic evaluation of 5.25% sodium hypochlorite gel and aqueous solution as root canal disinfectants in multirooted teeth with primary endodontic lesions. Following ethical approval and CTRI registration, 42 patients who gave their consent and had multirooted teeth with pulpal necrosis and asymptomatic apical periodontitis were considered for the study. Following the opening of the access, pre-endodontic build up in case of class-II cavities and working length determination, a pre-operative sample (S1), which was regarded as the pre-operative microbial load of that canal, was acquired from the largest canal using a sterile paper point while maintaining strict isolation and disinfection. The computer randomization approach was used to divide the teeth into two groups at random just before beginning of chemo-mechanical preparation: Group A (n = 21)—canal disinfection with 5.25% sodium hypochlorite gel; Group B (n = 21)—canal disinfection with 5.25% sodium hypochlorite aqueous solution. Following the canal disinfection, a post-operative (S2) sample which was regarded as the postoperative microbial load of that canal was collected from the same canal using a sterile paper point. The Colony-Forming Units (CFUs) for the S1 and S2 samples were determined after 48 h aerobic incubation on Brain Heart Infusion (BHI) agar plates. The patients and the microbiologist were blinded throughout the procedure. Using SPSS 20.0 software (USA), the Shapiro–Wilk test and the Lilliefors Significance Correction were used for normality, followed by the Mann–Whitney U test which was used to compare the CFU difference (×105) between the two groups. A p value of <0.05 was perceived as statistically significant. The mean colony-forming units count difference between the 5.25% sodium hypochlorite gel and aqueous solution groups did not differ in a manner that was statistically significant (p = 0.744). In multirooted teeth with primary endodontic lesions, the 5.25% sodium hypochlorite gel and the aqueous solution demonstrated comparable antimicrobial effectiveness when implemented as root canal disinfectants.
Aim:
To evaluate and compare the effect of conventional and truss access cavity preparations on remaining dentin thickness (RDT), canal transportation, and centering ability in mandibular molars using cone-beam computed tomography (CBCT).
Methods:
Ethical approval was obtained before the commencement of the study. Thirty extracted mandibular molars were selected, disinfected, and stored in normal saline. Preoperative CBCT scans were taken for all the samples and randomly divided into two groups. (n = 15). Group A; Conventional access preparation group; Group B; Truss access preparation group. Cleaning and shaping were performed with the mesiobuccal canal of all the samples. Postoperative CBCT scans were compared with preoperative CBCT scans to evaluate the RDT, canal transportation, and canal centering ability in mandibular molar with conventional and truss access cavity preparation.
Results:
Data obtained from CBCT were analyzed by independent sample t-test with the P < 0.05 and found that RDT was higher in Group A as compared to Group B at the 3 and 9 mm levels, whereas it was higher in Group B at 6 mm level in both the mesial and distal side, but it was statistically insignificant at 3, 6, and 9 mm level. Canal transportation was higher in Group B than in Group A, but it was statistically insignificant at 6 and 9 mm levels but statistically significant at 3 mm. Canal centering ability was higher in Group A than in Group B, but it was not statistically significant at 3, 6, and 9 mm levels.
Conclusion:
Regarding RDT and canal centering ability, there is no statistically significant difference at all levels. Both groups present a statistically significant difference at 3 mm from the apex when comparing canal transportation. This suggests that conventional access cavity preparation is better than truss access preparation to maintain original canal anatomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.