Este estudo teve por objetivo analisar a qualidade de vida do paciente com neoplasia hematológica submetido à quimioterapia. Realizou-se pesquisa quantitativa a partir da aplicação do questionário genérico WHOQOL-bref. A amostra foi composta de 16 pacientes do setor de ambulatório de quimioterapia de alto risco de um hospital de ensino do município de Curitiba-PR, no período de fevereiro a abril de 2010. Os resultados evidenciaram a prevalência do sexo masculino e a média de idade dos participantes esteve entre 20 e 64 anos. Entre os tipos de neoplasias hematológicas encontraramse 46,7% de leucemia linfocítica aguda, 33,3% de leucemia mieloide aguda e 20% entre linfoma não hodgkin, mieloma múltiplo e tricoleucemia. O período de tratamento foi de duas semanas a 24 meses e o número de sessões de quimioterapia foi entre uma e 80. Mediante análise, pode-se inferir que os domínios físicos e psicológicos foram os que sofreram mais alteração, porém sem diferença estatisticamente significativa para todos os domínios. Ressalta-se que o câncer altera indiscutivelmente todos os aspectos da vida do indivíduo e acarreta profundas alterações na sua rotina e hábitos de vida. Neste sentido, observam-se a necessidade e a importância do cuidado da enfermagem na intervenção desse processo. Palavras-chave: Enfermagem; Qualidade de Vida; Quimioterapia. ABSTR ACT This study aimed to analyze the quality of life of patients with hematological neoplasia undergoing chemotherapy. A quantitative research was carried out based on the application of the WHOQOL-bref generic questionnaire. The sample was composed of 16 patients in the outpatient high risk chemotherapy sector in a teaching hospital in the city of Curitiba-PR between February and April of 2010. The results showed a prevalence of males with ages between 20 and 64 years old. Among the types of hematological neoplasias, 46.7% were acute lymphocytic leukemia, 33.3% were acute myelogenous leukemia, and 20% were divided between non-Hodgkin's lymphoma, multiple myeloma, and hairy cell leukemia. The treatment period varied between 2 weeks and 24 months, and the number of chemotherapy sessions between 1 and 80. The analysis showed that the physical and psychological domains suffered the most changes, however, no statistically significant difference between all domains was observed. Cancer arguably changes every aspect of an individual's life and brings profound changes in their routine and habits of life. Thus, the necessity and importance of nursing care intervention in this process is observed.
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