Inflammation has been associated with Alzheimer's disease (AD) and dementia. The association between rheumatoid arthritis (RA) or arthritis and dementia/AD has been investigated in several case-control or hospital- and register-based studies with mixed results. This long-term population-based study investigates the association between presence of joint disorders (RA and other joint disorders) in midlife and cognitive status later in life. 1,449 participants were first evaluated in 1972, 1977, 1982, and 1987 and follow-up was performed after 21 years. A self-administered questionnaire including questions on joint disorders was used at both evaluations. Cognitive status (control, mild cognitive impairment, dementia/AD) was assessed at follow-up. The presence of any joint disorder in midlife was significantly associated with a worse cognitive status later in life: OR (95% CI) in an ordinal logistic regression analysis adjusted for age, gender, follow-up time, education, APOEε4, body mass index, smoking, drug treatment, and diabetes was 1.96 (1.17-3.28). For RA only, OR (95% CI) was 2.77 (1.26-6.10). The correlation remained significant for RA when AD was considered instead of dementia OR (95% CI) 2.49 (1.09-5.67). The presence of joint disorders, especially RA, at midlife seems to be associated with a worse cognitive status later in life. Given the chronic inflammatory component of RA, this study suggests that inflammatory mechanisms may have an important role in increasing the risk of cognitive impairment and dementia/AD.

Objectives:The aim of the current study is to investigate what males experience as helpful in their recovery process from eating disorders (ED).Methods: Qualitative in-depth interviews within a phenomenological approach, and using content analysis to excavate overarching text themes.Setting: Norway and Sweden. Participants: Included were 15 males with an age range from 19 to 52 years. Duration of illness varied between 3 and 25 years of experience with anorexia nervosa (n=10), bulimia nervosa (n=4) or ED not otherwise specified (n=1).

The aim of this study was to describe how former male patients perceive life after recovery from an eating disorder. A qualitative method with a phenomenographic approach was used to identify ways of experiencing recovery. Two descriptive categories were developed: body acceptance and self-worth. Six conceptions describe how recovered patients now relate in a balanced way to exercise and food, using strategies to avoid relapse. With a sense of self-acceptance and autonomy, they now appreciate their social life. Some perceive recovery as coping with remaining impulses to diet or exercise. Others experience themselves as totally free from the eating disorder.

The aim of this study was to identify and describe young women"s experiences of pelvic examination (PE). Qualitative interviews were conducted with nine women aged 18-23, who had undergone at least one PE. Data were analyzed using an interpretative phenomenological approach. Three general themes were identified: (1) relinquishing and regaining control, (2) facilitation of the situation by the examiner, and (3) PE is an unpleasant necessity. These general themes had a common structure that represented the essence: an intimate situation. The women experienced PE as an intimate situation, which they associated with their sexuality. They felt exposed both bodily and mentally, and were placed in a vulnerable situation. PE was considered as unpleasant, but necessary to confirm their health. During the PE, the women felt that they lost control of the situation by exposing their intimate parts. To regain control, the women felt a need for continuous information from the examiner. The vulnerable situation could be made less vulnerable if the examiner built a trusting relationship and made the women feel secure and seen as individuals. A deeper understanding of the situation from the women"s perspective could facilitate the examiner"s performance of PE, leading to more positive experiences among young women.

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The present study supports the earlier findings that depressive disorders among the very old are common, chronic and malignant. Mild depressive symptoms as indicated by GDS-15 score and history of stroke or hypertension seem to be important risk factors for incident depressive disorders in very old age.

Risk factors for incident dementia in the very old.International psychogeriatrics, 25 (7)

Our knowledge about males' perceptions about causes of eating disorder is very limited, but can be useful in the treatment planning for males. The aim of this study was to describe how male former patients perceived causes of onset of their eating disorder. Fifteen males previously treated for eating disorders and now considering themselves as recovered where interviewed at ages 19 -52. All interviews were recorded and analyzed qualitatively using a phenomenographic approach. Three categories of perceived causes of onset of eating disorders were found. The first category: self-dissatisfaction, was presented with three conceptions: "High achievements and demands", "Body-dissatisfaction" and "Low self-esteem". The second category: family environment, comprised the two conceptions: "Difficulty in family interaction and communication" and "Excessive expectations from family members". The third category was stressful events outside the family, and consisted of the three conceptions: "Bullying, bad situation at school", "Moving to new places/separation from friends" and "Societal ideals". Males' perceptions of causes of onset of their eating disorder were in many aspects similar to those earlier described for women. In treatment, it is important that the clinicians show a sincere interest in perceived causes, since it may facilitate a good working alliance with the patient.