Objective: To investigate the impact of household food insecurity during the third trimester of pregnancy on the growth indicators of infants aged less than six months. Design: Retrospective longitudinal study. Setting: 137 healthcare centres (15 cities) in Khorasan Razavi province, Iran. Data were extracted from the Sina Electronic Health Record System (SinaEHR®). Participants: This study was conducted on 2,481 mother and infant dyads during November 2016-March 2019. The household food insecurity access scale (HFIAS; nine-item version) was used to measure food insecurity in the third trimester of pregnancy. Women who delivered singleton infants were included in the study, and anthropometric indices of infants were measured throughout the first sixth months of life. Results: Approximately 67% of the participants were food-secure, while 33% had varying degrees of food insecurity. The children born to the mothers in the food-insecure households were respectively 2.01, 3.03, and 3.83 times more likely to be stunted at birth (95% CI: 1.17-3.46), four months (95% CI: 1.21-7.61), and six months of age (95% CI: 1.37-10.68) compared to their counterparts in the food-secure households. However, there were no significant differences in mean birthweight, birth height, and head circumference at birth between the two groups. Conclusions: Household food insecurity during pregnancy is a risk factor for stunting in infants aged less than six months. Therefore, national nutrition programs could considerably support women in food-insecure households during and before pregnancy.

Background and Objectives: Breast milk composition is affected by several factors such as maternal diet and body mass index. Milk fats include a major calorie content of the milk, which changes dramatically throughout the lactation. The aim of the present study was to assess breast milk fatty acid profile in overweight and obese mothers and its correlations with maternal body mass index.Materials and Methods: Milk samples were collected from 73 healthy lactating women referring to various health centers in Mashhad. Data were collected using food frequency questionnaire to assess the maternal dietary intakes. Breast milk fatty acid profile was assessed using gas chromatography.Results: Breast milk content of saturated fatty acids was higher in obese mothers than overweight mothers (p = 0.03) with positive correlations with maternal body mass index (r = 0.256; p = 0.037). Furthermore, breast milk monounsaturated fatty acids were negatively correlated with pre-pregnancy body mass index (r = -0.385; p = 0.003) and pre-pregnancy body weight (r = -0.276; p = 0.026). However, no significant correlations were observed between the maternal body fat mass and fat proportion with the breast milk fatty acids (p > 0.05). Moreover, no significant associations were seen between dietary saturated fatty acids, milk monounsaturated fatty acids, polyunsaturated fatty acids, n-3 polyunsaturated fatty acids and n-6 polyunsaturated fatty acids with the corresponding fatty acids in breast milk (p > 0.05). Conclusions:Based on the results, breast milk of the obese mothers included higher proportion of saturated fatty acids, while no significant differences were observed in the contents of milk monounsaturated fatty acids and polyunsaturated fatty acids between the overweight and obese women. Furthermore, maternal pre-pregnancy body mass index was negatively correlated with the contents of milk monounsaturated fatty acids, while it was positively correlated with saturated fatty acids contents.

BACKGROUND: The food frequency questionnaire (FFQ) is the method of choice for dietary assessment in epidemiological studies. FFQs focusing on mixed-dishes and simple food items are useful where mixed-dishes are an essential part of food consumption. OBJECTIVE: Regarding the fact that the nature of the Iranian diet is mixed-dish, the present study aimed to design and assess the validity and reproducibility of a dish-based semi-quantitative FFQ in the Iranian adult population. METHODS: A list of 302 food items was collected from four geographical areas around Iran. The validation study was conducted on 97 healthy adults. The FFQ was introduced at the beginning of the study and 10 months after; two three-day food records were collected during the study. Also, biomarkers including 24-hour urinary potassium and nitrogen, serum retinol, and alpha-tocopherol were measured. RESULTS: A 142-food-item FFQ was concluded. The correlation coefficient between the second FFQ and the second three-day food record ranged from 0.225 to 0.323 for macronutrients and 0.128 to 0.476 for micronutrients. The percentile agreements (same or adjacent quartile) between the two methods were more than 60%for all nutrients. The intraclass correlation coefficient between FFQs (except for vitamin E) ranged from 0.363 to 0.578. The correlation coefficient between the second FFQ and the second biomarker assessment was 0.241 for protein.