The most common reason for a decrease in the quantity and quality of produced crops is microbial diseases. This study evaluated the antifungal activity of Streptomyces sp. CACIS-16CA against few plant pathogenic fungi. Several fungal pathogens were tested using dual confrontation assays. The anti-fungal activities of CACIS-1.16CA and S. lydicus WYEC108 against Phytophthora capsici, Fusarium oxysporum, and Rhizoctonia solani were evaluated. Additionally, effect of bioactive extract (BE) from CACIS-1.16CA on the germination of conidia from various fungi was evaluated. Results indicated that Streptomyces sp. CACIS-16CA showed a higher percentage of anti-fungal activity (percentage of inhibition (PI), over 43%) than S. lydicus. Moreover, CACIS-1.16CA strain exerted higher percentage of inhibition (PI) against the three damping-off pathogenic fungi (P < 0,05). The BE of CACIS-1.16CA inhibited the conidial germination of Alternaria sp., Botrytis cinerea, and Colletotrichum spp. In conclusion, for the treatment of several plant fungal diseases, Streptomyces sp. CACIS-16CA may be an effective and natural alternative.
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