The aim of present study was to determine the antioxidant and anti-mycotoxin activities of crude ethanolic extracts from various organs of Bunium ferulaceum Sm. plant from Western Algeria. Firstly, we proceed to a phytochemical screening of leaves, kernels, and barks of plants. Tests showed the presence of several families of chemical constituents and phenolic compounds. The quantitative estimation of the total phenol content, flavonoids, and coumarins is carried out by colorimetric methods. The important total phenolic contents were found in leaves extract with a TPC value of 51.22 ± 0.46 mg GAE/g, whose flavonoids were revealed to be the main phenolic compounds in this extract and the coumarins in bark extract. The antioxidant activity was estimated by the DPPH method compared to the ascorbic acid antioxidant. The leaves extract showed a good scavenging activity with an IC50 value of 0.11 ± 0.57 mg/ml. Anti-mycotoxin activity are tested against three pathogens fungi produced mycotoxins using mycelial biomass assay and mycotoxigenic test. For all fungi tested, leaves extract showed the most inhibitory activity against Penicillium expansum MTTC 1344 and Aspergillus flavus MTTC 2799 followed by bark extract.
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