Coronavirus are coming under a broad family of virus that can cause respiratory illnesses such as the common cold, according to the centers for disease control and prevention (CDC). They are usual in many different species of animals, including camels and bats. Unusually, these corona viruses can evolve and infect humans and then spread between humans. Recent examples of this include SARS-CoV and MERS-CoV. 2019 Novel Corona virus (2019-nCoV) is a virus identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China. In some cases, the viruses can cause lower-respiratory tract illnesses such as pneumonia and bronchitis. In human corona viruses are currently classified into seven types that are HCoV-229E, HCoV-OC43, HCoV-NL63, SARS-CoV, HKU1, MERS-CoV and 2019-nCoV. These two types of corona virus (MERS-CoV and SARS-CoV) are more dangerous. Some of corona viruses like HCoV-229E, HCo-OC43, HCoNL63 and HKU1 that are continuously circulate in the population of human and cause respiratory infections in human either may children and adults world-wide. They are generally transmitted between animals and humans through sneezing, coughing, touching or shaking hands and making contact with a surface or object. The symptoms of corona virus are sneezing, cough, fatigue, runny nose, sore throat, breathing difficulty and exacerbated. In more severe cases SARS, kidney failure, pneumonia and even death. Diagnosis can be carried out by healthcare provider in laboratory test on respiratory specimens and serum to detect human corona virus. For this virus no specific treatment like vaccines and antiviral drugs but symptoms can be treated.
Selective serotonin reuptake inhibitors (SSRI's) are the most commonly prescribed antidepressants. They are mainly prescribed to treat depression. SSRI's are considered to be safer and generally cost effective when compared to some newer antidepressant classes. SSRI's acts by inhibiting the serotonin transporter (SERT) at the presynaptic axon terminal. A number of factors must be considered when evaluating SSRI's. An SSRI drug utilization study is performed for further evaluation. The study was a prospective obs Methodology: ervational study on “Utilization and Evaluation of SSRI's in Psychiatry Patients”, which was carried out in the 'Department of Psychiatry' in a Secondary care teaching hospital of South India. Study the maximum number of patients was 786 and the age groups of 981 out of which m Results: aximum were of age group 46-54 and minimum were above 60, the female were more suffered in that maximum were married and the educational levels of the patients were mostly secondary, the hygienic conditions, surroundings and cleanliness were good. Discussion: Recent studies also found that mostly used SSRIs are Fluoxetine, Paroxetine, Citalopram and Sertraline. We found that in our hospitals the data reveals the status for some mostly used Fluoxetine as 386 (49.10%) and Paroxetine 288 (36.64%). Conclusion: Our study concluded that most of the patients suffered with psychological conditions and symptoms are considered. After using SSRI their overall effect in the patient health and outcome was observed with better outcome.
Background: Organophosphate poisoning is poisoning due to organophosphates (OP’s), used in insecticides, medications and nerve agents. It occurs mostly during suicide attempts in the farming areas, developing world and less by accident. The study is to evaluate the drugs used, respiratory conditions, complications occurred during course of treatment.Methods: This was a prospective observational study conducted for 9 months in a tertiary care hospital. The study was conducted in a 500 bedded tertiary care hospital in an intensive care unit. The study was conducted for nine months (September 2016 - May 2017).Results: A total of 234 patients who had consumed OPP with known and unknown agents were admitted in the emergency department. Out of which 180 males and 54 females.Conclusions: This study concluded that the patients consumed poison is mainly due to mental disturbances and financial problems. The stress and burden on the life will shows the effect after consumption, the maximum people suffer with respiratory problems due to poison consumption. If the government should take the measures to avoid consumption of poison and availability of poison to the public may overcome the complications and reduce the deaths due to poison.
AIM: Aim of the study is to determine the effect of oral sodium bicarbonate in maintaining acid base balance and quality of life in chronic kidney disease and long-term acidosis patients. Study Design: A prospective observational study. Study Population: Approximately 174 people who came to nephrology department, Selected based upon inclusion and exclusion criteria. Study Criteria / Patient Enrollment: Patients are enrolled in study based on inclusion and exclusion criteria. Inclusion Criteria: The patients who are diagnosed with CKD and receiving oral sodium bicarbonate as part of treatment Exclusion Criteria: the patients who are having other comorbidities, hypertension, diabetes, and other cardiovascular problems who are not given with oral sodium bicarbonate. Study Duration : 6 months (December 2021- May 2022). Methodology: A prospective observational study on effect of oral sodium bicarbonate in maintaining acid base balance and quality of life in chronic kidney disease and long term acidosis patient’s which was carried out in the Department of nephrology. Results: Most of the patients are in between the age of 70-80 years, married, with good nutritional status, with minimum 5 months of CKD, approximately 50%of the patients are suffering from HTN along with CKD followed by diabetes. Patients are using OSB for a minimum of 5 months with 500mg dose given thrice a day, along with Calcium channel blockers and pantoprazole. OSB is given as a oral tablet. Conclusion: Oral bicarbonate is widely used to correct acidosis in advanced CKD, this is not underpinned by trial evidence, and real uncertainty exists regarding the balance of benefit and risk for this intervention. That we concluded that most of the patients using OSB was analyzed from nephrology department in QOL, in maintaining acid-base balance was observed in CKD patients.
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