The electrogastrogram is abnormal in approximately 36% of functional dyspepsia patients and has a specificity of approximately 93%. Electrogastrography defines a subgroup of patients with functional dyspepsia and electrical rhythm disturbance. In irritable bowel syndrome, the electrogastrogram is usually abnormal only if concurrent dyspepsia is present.
The electrogastrogram is abnormal in approximately 36% of functional dyspepsia patients and has a specificity of approximately 93%. Electrogastrography defines a subgroup of patients with functional dyspepsia and electrical rhythm disturbance. In irritable bowel syndrome, the electrogastrogram is usually abnormal only if concurrent dyspepsia is present.
INTRODUCTIONNon-ulcer dyspepsia (NUD) is characterized by persistent or recurrent epigastric symptoms including pain and fullness, early satiety, nausea, and/or vomiting that are not explained by structural or biochemical abnormalities. 1 Recent studies have indicated that NUD might be a result of abnormalities in gastric physiology. NUD patients demonstrate a reduced sensory threshold to gastric distension compared to controls. 2±4 Motor abnormalities include a decreased antral and/or antroduodenal contractile response to the ingestion of a meal or uncoordinated and/or non-propagated duodenaljejunal motor waves. 5,6 These abnormalities of gastric motor physiology are often accompanied by delayed gastric emptying 7±10 and maldistribution of food in the stomach. 11 The maldistribution of food may also be related to impaired gastric accommodation, 2 resulting in increased food loading of the antrum following a meal. The electrogastrogram (EGG) is a non-invasive test used to measure gastric myoelectrical activity. Normal gastric myoelectrical activity consists of a slow wave and spike potentials. The EGG accurately records the slow wave, which controls the velocity and propagation of gastric contractions. Previous studies have demonstrated that the EGG is reproducible and stable over time. 12 In addition, the EGG is not affected by age or gender. 13 The EGG detects gastric dysrhythmias, either fast frequency waves (tachygastria) or slow frequency waves (bradygastria). Studies using serosal transducers and manometry have shown that tachygastrias correlate with absent antral contractions 14 and bradygastrias are associated with both strong and or absent antral SUMMARY Background: The electrogastrogram (EGG), which records gastric myoelectrical activity, is abnormal in onethird of adult patients with non-ulcer dyspepsia (NUD). Aim: To observe the effects of cisapride on EGG in adults with NUD. Methods: Twenty-seven NUD patients who had undergone a pre-and post-prandial EGG were entered into an open study. All patients completed a dyspepsia symptom questionnaire and were then treated with cisapride 10 mg t.d.s. The dyspepsia questionnaire was repeated in all those completing 4 weeks of treatment. Those with an initial abnormal EGG (< 70% of slow wave
The electrogastrogram (EGG) is a noninvasive method of recording gastric myoelectrical activity. The activity is detected by positioning cutaneous electrodes over the upper abdomen and capturing the mean electrical frequency of the gastric pacemaker. Normal gastric myoelectrical activity consists of a slow wave and spike potentials. The EGG records the slow wave, which controls the velocity and propagation of gastric contractions. This oscillates within a narrow frequency band, and any gastric activity outside this band is designated a dysrhythmia.Gastric dysrhythmias consist of fast frequency (tachygastrias) and slow frequency (bradygastrias) waves. Studies using serosal transducers and manometry have shown that tachygastrias correlate with absent antral contractions.1 2 Bradygastrias have been reported to associate with both strong or absent antral contractions.
Introduction Diverticulitis, the common clinical complication of diverticulosis, may affect 10%e25% of patients with colonic diverticula. The diagnosis of diverticulitis may be made on clinical grounds. However, it is usual practice to perform a CT scan to confirm the diagnosis and assess for complications (eg, abscess, fistula, obstruction). CT criteria suggestive of diverticulitis include: presence of diverticula with pericolic infiltration of fatty tissue, thickening of the colonic wall, and abscess formation. The sensitivity of CT scan in diagnosing of diverticulitis is up to 97%. Once an episode of diverticulitis has been treated, we have observed patients to be followed up by undergoing routine colonoscopy (CSy). We hypothesised that the value of CSy in patients with a confirmed CT diagnosis of diverticulitis is negligible. Methods A duel centre (2 North London hospitals), retrospective analysis of all patients with an ICD 10 coding on their in-patient discharge summary letters of diverticular disease (DD) over the past year was employed. Patient notes were scrutinised and correlated to endoscopic records. The dates of both CT scan and CSy were recorded. Completion rates of the endoscopies and findings in addition to diverticular disease was noted.Results 137 patients over a 4-month period had DD recorded within the discharge summary. 47 patients with presumed diagnosis of diverticulitis had a CT scan prior to endoscopy (35 CSy and/12 Flexible sigmoidoscopy). Of the 47, DD was evident on the CT scan in 34. Endoscopy subsequently confirmed DD in 32/34 of these cases (95%), with four procedures ending in failure. No other pathological features were found in 30/34 cases. Within the cohort of 32 patients in which endoscopy confirmed CT, three had colonic polyps. Of the 13 cases (of 47) in which DD was not reported on the prior CT scan, subsequent endoscopy confirmed DD in 11/13, with one procedure ending in failure. Of these 11 cases, one had a colonic polyp. In the two cases where endoscopy did not reveal DD, a diagnosis of colitis was recorded. Conclusion In this study, performing a CSy in patients previously diagnosed with diverticulitis confirmed on CT scan add no further information. CSy is only useful in the setting of clinical diverticulitis if the diagnosis is not supported by CT scan. In patients with diverticulitis other diagnosis such as polyps were detected in only 4 of 47 patients (8%), not a unsurprising finding as one would expect to find polyps at routine CSy in upto 25%. From this study, we would not support performing a CSy in patients with clinical diverticulitis confirmed on CT scan and avoiding CSy could save 100 colonoscopies per annum in a hospital like ours freeing up space to perform other procedures with more appropriate indications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.