Optical emission spectroscopy (OES) is a common method for characterizing radio frequency (RF) discharge plasmas. Particulary, helicon plasma is featured by its high plasma density among all RF-excited plasmas. In order to obtain the spatial-resolved information of a helicon plasma, local optical emission spectroscopy (LOES) with a 3 mm spatial resolution was proposed and carried out to evaluate the local electron density and temperature. The plasma emission intensity via LOES was measured and compared with the electron density obtained by a RF-compensated Langmuir probe (LP) in Ar, N 2 and Air helicon plasmas, respectively. The results revealed that there existed a functional relationship between some specific lines (LOES) and electron density (LP). Further, helicon plasma characteristics under capacitive (E) , inductive (H), and helicon (W) modes were systemetically investigated based on LOES. Besides, two-dimensional (2D) contour maps for plasma distributions were made via LOES as well. It was found that in E-and H-modes, axial profiles of plasma density and electron temperature were consistent under two opposite magnetic field directions. However, in W-mode, the plasma presented an asymmetric axial profile along the tube. As for radial profiles, plasma distribution varied under three discharge modes due to different heating mechanisms in Ar, N 2 or Air helicon plasma. A deeper analysis indicated that the bulk absorption comes from the coupling of the helicon wave in Ar helicon plasma while the power depositions in N 2 and Air helicon plasma are mainly dominated by the TG wave.

We present the axial profiles of argon helicon plasma measured by a local optical emission spectroscope (OES) and Langmuir RF-compensated probe. The results show that the emission intensity of the argon atom lines (750 nm, 811 nm) is proportional to the plasma density determined by the Langmuir probe. The axial profile of helicon plasma depends on the discharge mode which changes with the RF power. Excited by helical antenna, the axial distribution of plasma density is similar to that of the external magnetic field in the capacitive coupled mode (E-mode). As the discharge mode changes into the inductively coupled mode (H-mode), the axial distribution of plasma density in the downstream can still be similar to that of the external magnetic field, but becomes more uniform in the upstream. When the discharge entered wave coupled mode (W-mode), the plasma becomes nearly uniform along the axis, showing a completely different profile from the magnetic field. The W-mode is expected to be a mixed pattern of helicon (H) and Trivelpiece-Gould (TG) waves.

Prostate cancer is the most common cancer and one of the leading causes of cancer mortality in males. Androgen-deprivation therapy (ADT) is an effective strategy to inhibit tumour growth at early stages. However, 10~50% of cases are estimated to progress to metastatic castration-resistant prostate cancer (mCRPC) which currently lacks effective treatments. Clinically, salvage treatment measures, such as endocrine therapy and chemotherapy, are mostly used for advanced prostate cancer, but their clinical outcomes are not ideal. When the existing clinical therapeutic methods can no longer inhibit the development of advanced prostate cancer, human adenovirus (HAdV)-based gene therapy and viral therapy present promising effects. Pre-clinical studies have shown its powerful oncolytic effect, and clinical studies are ongoing to further verify its effect and safety in prostate cancer treatment. Targeting the prostate by HAdV alone or in combination with radiotherapy and chemotherapy sheds light on patients with castration-resistant and advanced prostate cancer. This review summarizes the advantages of oncolytic virus-mediated cancer therapy, strategies of HAdV modification, and existing preclinical and clinical investigations of HAdV-mediated gene therapy to further evaluate the potential of oncolytic adenovirus in prostate cancer treatment.

The electric double layer in argon helicon plasma by using floating electrostatic probe and local optical emission spectroscopy under different external magnetic field was investigated. Results show that electrons generated in the plasma source can be magnetized by the magnetic field and transported by the gradient of diverging magnetic field in the diffusion chamber, giving rise to the hollowed distribution of electron temperature. The electron temperature on axis has a sudden decrease, leading to the sudden decrease of plasma density as well as the plasma potential, forming a double layer structure. The position of double layer moves along with the position of diverging magnetic field, and the potential drop increases along with the strength of magnetic field. The structure of the external magnetic field plays the decisive factor for the double layer in helicon plasma.

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Since the Chinese Education Disciplinary Rules for Primary and Secondary Schools (Trial), i.e., The Trial Rules (TTR) was first put into practice, its implementation has been limited because of teachers’ ignorance and misconduct. A comparative study is needed to shed light on these issues and promote TTR policies. As a country based on case law and a centralised educational system, England represents an appropriate reference. The present study compares the history and latest regulations in education between two countries (England and China) in terms of the participants and processes involved in education discipline. It is important to note that TTR has a shorter history than the system in England, and therefore, it provides relatively limited guidance for classroom teachers because there has not been enough practical or theoretical feedback. However, considering the regulations about the education disciplinary process (e.g., deviance, discipline, and feedback), TTR has formed a relatively well-developed stipulations for the latter two steps, while further details must be developed to better address deviance. Overall, more referential cases are needed as guidance for teachers.