Introduction: Hypertension is growing among the population of Nepal. We aimed to determine the current knowledge, attitude and practice of hypertension among hypertensive patients taking antihypertensive medication in the community of Central Nepal.Methods: A cross-sectional study was conducted among the hypertensive patients in Bharatpur, Chitwan, Nepal from July 2015 to September 2015 using clustered sampling technique. Suitably designed and validated questionnaire of knowledge, attitude and practice on hypertension consisting of 27 questions were used to determine the KAP scores. The difference in the median KAP scores between sex, level of education and duration of hypertension were assessed using Mann-Whitney U test.Results: A total of 200 patients met the inclusion criteria and majority of them were male (60%), had received primary education (36%) and had hypertension for ≥5 years (46.5%). The blood pressure ranged from 100-180/60-110 mmHg. The median K, A and P scores were 8 (6), 5 (1) and 6 (3) respectively. K and A were statistically associated with sex both at p<0.001 and level of education (K at p<0.001 and A at p=0.016).Conclusions: The current knowledge, attitude and practice among hypertensive patients using antihypertensive medication can be improved. Keywords: attitude; hypertension; knowledge; practice. | PubMed

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Adverse Drug Reactions (ADRs) are a global problem adding to the economic burden of the society. Anti-cancer drugs are prone to cause ADRs and there is lack of pharmacovigillance data on such type drugs. Therefore, the present study was undertaken to monitor suspected ADRs in the cancer chemotherapy with its management in B.P. Koirala Memorial Cancer Hospital (BPKMCH). The study was done in the inpatient department of BPKMCH from May, 2014 to July, 2014, among the patients receiving chemotherapy. It was a hospital based prospective observational study. Most commonly occurring cancer were lung (16%), ovary (15%), cervix (11%), breast, blood, and throat (9%). Most frequently used drugs for cancer chemotherapy were paclitaxel (25%), cyclophosphamide (18%), vincristine (9%), cisplatin (11%) and adriamycin (6%). Most common ADRs experienced were nausea & vomiting (85.45%), loss of appetite (72.72%), mucositis (65.45%), pain (63.63%), loss of breath (40%), constipation (52.72%) and polyneuropathy (58.18%). DOI:http://dx.doi.org/10.3126/jcmc.v4i4.11967

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