The behavior of denaverine (1) in various chemical model systems based on metalloporphyrins as catalysts was investigated to determine the possible oxidative metabolism. The resulting derivatives were compared to a biological model system and in vivo metabolism in rat and human.
Keywords: Biomimetic oxidations / Cytochrome P450 / Metalloporphyrins / Denaverine / MetabolismThe behavior of denaverine (1) in various chemical modelThe resulting derivatives were compared to a biological model system and in vivo metabolism in rat and human. systems based on metalloporphyrins as catalysts was investigated to determine the possible oxidative metabolism.
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