ObjectiveWe sought to explore the prevalence and immediate clinical implications of acute myocardial injury in a cohort of patients with covid-19 in a region of China where medical resources are less stressed than in Wuhan (the epicentre of the pandemic).MethodsWe prospectively assessed the medical records, laboratory results, chest CT images and use of medication in a cohort of patients presenting to two designated covid-19 treatment centres in Sichuan, China. Outcomes of interest included death, admission to an intensive care unit (ICU), need for mechanical ventilation, treatment with vasoactive agents and classification of disease severity. Acute myocardial injury was defined by a value of high-sensitivity troponin T (hs-TnT) greater than the normal upper limit.ResultsA total of 101 cases were enrolled from January to 10 March 2020 (average age 49 years, IQR 34–62 years). Acute myocardial injury was present in 15.8% of patients, nearly half of whom had a hs-TnT value fivefold greater than the normal upper limit. Patients with acute myocardial injury were older, with a higher prevalence of pre-existing cardiovascular disease and more likely to require ICU admission (62.5% vs 24.7%, p=0.003), mechanical ventilation (43.5% vs 4.7%, p<0.001) and treatment with vasoactive agents (31.2% vs 0%, p<0.001). Log hs-TnT was associated with disease severity (OR 6.63, 95% CI 2.24 to 19.65), and all of the three deaths occurred in patients with acute myocardial injury.ConclusionAcute myocardial injury is common in patients with covid-19 and is associated with adverse prognosis.
Interactions between oxygen and gold surfaces are fundamentally important in diverse areas of science and technology. In this work, an oxygen dimer structure was observed and identified on gold nanoparticles in catalytic decomposition of hydrogen peroxide to oxygen and water. This structure, which is different from isolated atomic or molecular oxygen surface structures, was observed with in situ surface-enhanced Raman spectroscopic measurements and identified with density functional theory calculations. The experimental measurements were performed using monodisperse 5, 50 and 400 nm gold particles supported on silica with liquid-phase hydrogen and deuterium peroxides at multiple pH values. The calculations show that on surfaces with coordinatively unsaturated gold atoms, two oxygen atoms preferentially share a gold atom with a bond distance of 0.194-0.196 nm and additionally bind to two other surface gold atoms with a larger bond distance of 0.203-0.213 nm, forming an Au-O-Au-O-Au structure. The formation of this structure depends on reaction rates and conditions.
Interactions
between oxygen and silver are important in many areas
of science and technology, including materials science, medical, biomedical
and environmental applications, spectroscopy, photonics, and physics.
In the chemical industry, identification of oxygen structures on Ag
catalysts is important in the development of environmentally friendly
and sustainable technologies that utilize gas-phase oxygen as the
oxidizing reagent without generating byproducts. Gas-phase oxygen
adsorbs on Ag atomically by breaking the O–O bond and molecularly
by preserving the O–O bond. Atomic O structures have Ag–O
vibrations at 240–500 cm–1. Molecular O2 structures have O–O vibrations at significantly higher
values of 870–1150 cm–1. In this work, we
identify hybrid atomic-molecular oxygen structures, which form when
one adsorbed O atom reacts with one lattice O atom on the surface
or in the subsurface of Ag. Thus, these hybrid structures require
dissociation of adsorbed molecular oxygen into O atoms but still possess
the O–O bond. The hybrid structures have O–O vibrations
at 600–810 cm–1, intermediate between the
Ag–O vibrations of atomic oxygen and the O–O vibrations
of molecular oxygen. The hybrid O–O structures do not form
by a recombination of two adsorbed O atoms because one of the O atoms
in the hybrid structure must be embedded into the Ag lattice. The
hybrid oxygen structures are metastable and, therefore, serve as active
species in selective oxidation reactions on Ag catalysts.
Passive indoor localization techniques can have many important applications. They are nonintrusive and do not require users carrying measuring devices. Therefore, indoor localization techniques are widely used in many critical areas, such as security, logistics, healthcare, etc. However, because of the unpredictable indoor environment dynamics, the existing nonintrusive indoor localization techniques can be quite inaccurate, which greatly limits their real-world applications. To address those problems, in this work, we develop a channel state information (CSI) based indoor localization technique. Unlike the existing methods, we employ both the intra-subcarrier statistics features and the inter-subcarrier network features. Specifically, we make the following contributions: (1) we design a novel passive indoor localization algorithm which combines the statistics and network features; (2) we modify the visibility graph (VG) technique to build complex networks for the indoor localization applications; and (3) we demonstrate the effectiveness of our technique using real-world deployments. The experimental results show that our technique can achieve about 96% accuracy on average and is more than 9% better than the state-of-the-art techniques.
A diode-pumped femtosecond mode-locked Nd,La:CaF 2 disordered crystal laser was reported for the first time. By appropriately choosing the Nd and La-doping concentration, stable mode-locked femtosecond laser pulses were obtained by using a semiconductor saturable absorber mirror (SESAM). The laser produced 633 fs pulses at the central wavelength of 1061 nm with an average output power of 200 mW at 82 MHz repetition rate.
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