This investigation lies within the framework of studying the phytochemistry of two medicinal plants Tithonia diversifolia and Tephrosia vogelii and assessing their potentials in controlling the helminthiasis in goats. The crude extracts were obtained from the leaves by Soxhlet methodology and phytochemical screening, fecal eggs reduction and the anthelmintic activities were tested in various laboratories in Butare. The results from this investigation showed that both T. diversifolia and T. vogelii have lots of active principles grouped in alkaloids, tannins, flavonoids, terpenoids,and sterols and exhibit anthelmintic activities in goats. The percentages of reduction of fecal eggs are 98, 97, 96 and 95% with methanol crude extract of T. vogelii, infusion of T. vogelii, methanol crude extract of T. diversifolia and infusion of T. diversifolia, respectively. This investigation showed the efficacy of both T. vogelii and T. diversifolia against gastrointestinal nematodes in goats and therefore their potentials in assuring more the animal health care in Rwanda by for treating the parasitic nematodes in goats by plant-based drugs instead of crude extracts.
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