Aim
The incidence of cutaneous squamous cell carcinoma (cSCC) in Asians remains low but shows a steady rising trend. There is a lack of reporting of the long‐term outcome in this population. This study aims to evaluate the 5‐year overall survival and its associated prognostic factors among patients with head and neck cSCC.
Patients and Methods
Patients with head and neck cSCC were identified in a regional hospital over 20 years. The 5‐year overall survival was estimated with the Kaplan–Meier curve and its prognostic risk factors were analysed using Cox proportional hazard regression.
Results
A total of 73 patients were identified. The median age was 84. The 5‐year overall survival rate was 40.3%. A higher grade of differentiation (hazard ratio 3.732, 95% confidence interval 1.161–11.991, P = .027) was a significant prognostic factor on both univariate and multivariate analyses.
Conclusion
In this Asian cSCC survival series specific to the head and neck region, which mostly included octogenarians, the 5‐year overall‐survival was low and a poor grade of differentiation was associated with a worse survival. Further studies on the Asian population is warranted.
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