Poster session 3, September 23, 2022, 12:30 PM - 1:30 PM
Background: Invasive aspergillosis has increased in the last decade. They mainly occur in neutropenic patients (following anticancer treatment) and in patients treated with immunosuppressants and corticosteroids. The galactomannan antigen in serum appears to be a serological method able to aid in the diagnosis of invasive aspergillosis also the antigen detection in bronchoalveolar lavage has proven to be advantageous for the diagnosis of invasive aspergillosis.
Objectives:
Methods
A total of 175 samples were collected from patients suspected to have fungal infections from the period of January 2018 to March 2022 from a tertiary care center in South India. The galactomannan assay and culture were done for these samples. Data of age, sex, gender, diagnosis, underlying conditions, antifungal treatment, and outcomes were collected.
Results
Out of 175 samples collected from patients suspected with Aspergillosis, 120 were males and 55 were females (7 were repeat samples).
The major underlying conditions were diabetes and hypertension, coronary artery disease (CAD), and Hematopoetic malignancy such as B Cell lymphomas, ALL, and AML (Fig. 1).
Conclusion
Galactomannan alone cannot be taken as a diagnostic marker. Clinical correlation, radiologic findings, as well as underlying risk factors play a major role for decision on the initiation of empiric treatment.
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