Due to attractive application in the medical field, fiber Bragg grating sensor has become increasing attractive from past few decades for various strain sensing applications. FBG sensor has been used in many applications such as different surgical devices, vital sign detection devices, invasive surgery, heart rate, dental applications and biosensing application as wearable sensing devices. This paper reviews the 55 recent research articles published on fiber Bragg grating sensor for biomedical application used the qualitative, quantitative and experimental method to identify the recent advancement and challenges. In this study, particular focus is placed on applications for biomechanical devices, temperature monitors, respiratory monitors, and biosensing applications. Critical things, demands, and emerging trends for these sensing devices are also discussed in order to determine what will be needed for the next generation.