Introduction. Interstitial lung diseases in newborns associated with diffuse pulmonary developmental disorders are a difficult to detect, as they are rare, formed at the early stages of embryonic development, clinically manifested in the first hours of life as severe respiratory distress syndrome in newborns. The aim. To demonstrate the role of radiation research methods and the difficulties of differential diagnosis of rare forms of interstitial lung diseases associated with diffuse impaired lung development. Materials and methods. Clinical cases of congenital alveolar dysplasia and alveolar-capillary dysplasia with an abnormal location of the pulmonary veins are described in detail, the radiological data, confirmed by the histological data, are presented. Results. Specific changes in the lungs in ILD of newborns associated with a diffuse disorder of lung development, according to X-ray data in the first day of life, are not determined, however, a progressive negative trend has been noted. The lungs computed tomography allows a detailed diagnosis of structural changes in the lung parenchyma, their severity and prevalence. Issues of differential diagnosis of diffuse disorders of lung development in newborns are discussed; the obtained results correlate with the published data. Conclusions. Histological examination is the “gold standard” in the diagnosis of interstitial lung diseases associated with diffuse lung developmental disorders in newborns, but is most often performed at autopsy. The role of radiological methods in the algorithmic approach of diagnostics is increasing due to the accumulated data, the improvement in the quality of detection and recognition of rare variants of interstitial lung diseases in newborns according to CT of the chest organs.
The paper presents a case of a single bronchocele (bronchogenic retention cyst) caused by a typical carcinoid that was observed for a long time. During the initial complex examination, including computed tomography with intravenous contrast, fibrobronchoscopy, and immunological and bacteriological examinations of tuberculosis, there were no changes for the oncological and infectious nature. The changes were interpreted as the result of a postponed nonspecific inflammatory process. Most of them were monitored using chest X-ray and the changes were stable. After 15 years, a control chest X-ray revealed an increase in the size of the compaction in the lung and the appearance of a mass with calcification in the medial sections of the compaction zone. Additional examination, including computed tomography with biopsy, determined that the obstruction of the bronchus was caused by a neoplasm [according to histological examination (typical carcinoid)]. It should be noted that the initial detection of negative study results requires oncological alertness and periodic examinations in dynamics.
Aim of the study: to evaluate the possibilities of differential diagnosis of cystic metastases of pancreatic cancer in the lungs and pulmonary Langerhans cell histiocytosis (PLCH)Materials and methods. Multiple cysts were visualized in the patient's lungs, which had thin and thick walls. We visualized in the patient's lung several small nodes with random distribution. These changes were located mainly in the upper and middle sections of the lungs, with the presence of several cysts and nodes near the costal-diaphragmatic angles. The differential diagnosis is formed from metastatic lung disease and pulmonary Langerhans cell histiocytosis. Morphological verification of changes in the lungs confirmed metastatic lung disease.Conclusion. A careful assessment of the thickness of the walls of cysts and the type of location of nodes in the patient's lungs made it possible to diagnose metastatic lung disease according to CT scans.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.