Aim: This study aimed to clarify the ultrasound semiotics of colorectal cancer liver metastases contrast enhancement, and perform a comparative assessment of the diagnostic efficacy of contrast-enhanced ultrasound and computed tomography (CT).Methods: We studied 40 patients with colorectal cancer: patients receiving treatment for the disease and having newly diagnosed colorectal cancer. All patients underwent contrast-enhanced ultrasound and CT. In the cases of suspected malignancy, a trephine biopsy and a morphological examination were performed.Results: Contrast-enhanced ultrasound and CT demonstrated comparable and high diagnostic efficacy. The sensitivity of the contrast-enhanced ultrasound in malignancy detection was 93.3%, with 90% specificity, 96.55% positive predictive value, 81.82% negative predictive value, and 92.5% accuracy. The sensitivity of contrast-enhanced CT was 93.3%, with 80% specificity, 93.33% positive predictive value, 80% negative predictive value, and 92.5% accuracy.Conclusions: For patients with colorectal cancer with contraindications to contrast-enhanced CT, contrast-enhanced ultrasound may be used an alternative imaging option for the differential diagnosis of liver neoplasms.
Purpose: To compare the capabilities and evaluate the effectiveness of gray-scale B-mode, Doppler mapping and contrast enhanced in the assessment of cystic renal lesions.Material and methods: Ultrasound examination (US) was performed in 61 patients with cystic kidney formations (category Bosniak ≥ II). Cysts of categories Bosniak ≥ III were histologically verified, rest (categories II–IIF) were under follow up. All patients underwent gray-scale ultrasound, color Doppler imaging and contrast enhanced (CEUS).Results: The efficiency of the B mode was: sensitivity 55.6 %; specificity 72.1 %; accuracy 62.3 %, in the CDI mode these indicators were 52.8; 80.1; 63.9 %, respectively. Contrast ultrasound significantly increased the capabilities of the method, and also made it possible to evaluate cystic formations according to the Bosniak criteria with indicators of the effectiveness of the method up to 100.0; 92.0; 96.7 %, respectively.Conclusions: CEUS demonstrated high informative value in the assessment of renal cystic formations in comparison with native ultrasound and Doppler modes, and therefore the technique should be considered as promising for inclusion in the algorithm of examination of complex renal cysts.
Objective: to evaluate the effectiveness and capabilities of multiparametric ultrasound (mpUS) with contrast enhanced in the assessment of renal cystic lesions and compare data with the results of computed tomography (CT).Patients and Methods. The study included 61 patients with cystic kidney tumors (category Bosniak ≥ II). Cysts of categories Bosniak ≥ III were morphologically verified, the rest (categories II-IIF) were under long-term dynamic control. All patients underwent mpUS including greyscale mode, color doppler imaging (CDI) and contrast-enhanced ultrasound (CEUS), as well as contrast-enhanced CT.Results. Contrast-enhanced mpUS with CEUS demonstrated high efficiency of the method: sensitivity (Se) – 97.2%; specificity (Sp) – 91.6%; accuracy (A) – 95.1%. The effectiveness of CT with contrast in the study group was 91.7%; 84.0%; 88.5% respectively. Also, mpUS showed a more accurate assessment of cystic tumors according to the Bosniak classification, in comparison with contrast-enhanced CT.Conclusions. Contrast-enhanced mpUS with CEUS demonstrated a significant increase in the effectiveness of the method as a whole, as well as higher rates in comparison with CT in the assessment of cystic formations of the kidneys. This technique should be considered as the method of choice in cases where CT is not possible, and it is recommended to include it in the algorithm for examining patients with cystic kidney tumors.
Most often any kidney lesions are primary renal, but sometimes they can be secondary (metastases, lymphoma). Every year renal cell carcinoma tends to a significant increase in the incidence. Today there are many available methods of examination, however difficulties often remain in the differential diagnosis of kidney lesions. The article discusses about the modern possibilities of methods in the identification and assessment of kidney lesions, their role in determining the tactics of patient management and key approaches in imaging characterization of these masses using CT and PET, MRI and CEUS. The analysis of the modern literature has shown that the currently existing radiation diagnostic methods do not provide an absolute opportunity for differential diagnosis of rare kidney tumors. CEUS, according to various authors, demonstrates high efficiency indicators, but does not exceed these indicators in comparison with CT and MRI. Contrast-enhanced ultrasound is a potentially safe method and can be used as a method for additional examination to characterize indeterminate renal lesions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.