Relevance. The prevalence of post-traumatic stress disorder ranges from 1 to 12 % among the general population and reaches 30 % among the population affected by various emergencies, which makes the PTSD problem ever more relevant considering the special military operation in Ukraine.Objectives. The aim is to study and describe the main clinical approaches to the treatment of PTSD.Methods. The clinical and bibliographic method were used to perform a comparative analysis of academic research papers published in 2008 to 2022.Results and discussion. Treatment of PTSD requires an interdisciplinary approach with a particular focus on individually specific psychotherapeutic methods, as well as administration of selective serotonin reuptake inhibitors (SSRIs) as antidepressants. We analyzed clinical and diagnostic aspects of combat PTSDs, their pathology, origin, treatment options and challenges for discussion. Currently, combat PTSDs are acquiring extra relevance.Conclusion. While trying to investigate the development of clinical PTSD manifestations, the focus is shifted from syndrome-associated parameters towards understanding PTSD as an integral disorder of psychogenic origin with polysyndromic and multisystemic characteristics.
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