Objectives The purpose of the study is to determine the level of serum uric acid (s. uric acid) above which all complications occur, to analyze the maternal and fetal clinical and laboratory changes associated with elevated s. uric acid, and to determine whether s. uric acid can be used to predict maternal and fetal complications. Design A retrospective study of hospital records was done on 80 women of pregnancy induced hypertension including both gestational hypertension and preeclampsia from January 2011 to March 2012 at Civil Hospital, Ahmedabad. The women were divided in two groups: with s. uric acid > 6 mg/dl/ s. uric acid < 6 mg/dl. Results S. uric acid > 6 mg/dl was associated with maternal complications while s. uric acid > 5.5 mg/dl was associated with low birth weight babies. The mean creatinine and platelet count in two groups were significantly different at 5% level. Statistically significant elevation of s. uric acid was found in women of eclampsia. Conclusion S. uric acid > 6 mg/dl is associated with increased maternal complications specially eclampsia and higher incidence of low birth weight. Thus, women with pregnancy induced hypertension with s. uric acid > 6 mg/dl should be offered termination of pregnancy. How to cite this article Sahijwani D, Desai A, Oza H, Kansara V, Ninama P, Maheshwari K, Soni C, Padhiyar B. Serum Uric Acid as a Prognostic Marker of Pregnancy induced Hypertension. J South Asian Feder Obst Gynae 2012;4(3):130-133.
Lung ultrasound (LUS) has been proven to yield valuable information for lung and pleural pathology. It is well validated for assessing extravascular lung water. It can also be used to monitor stages of controlled lung de-aeration in whole lung lavage (WLL) which is the treatment for Pulmonary Alveolar Protienosis (PAP),characterized by abnormal surfactant in the alveoli affecting gas exchange .LUS can help decide the point of termination of lung flooding. A 55 year old lady with biopsy proven pulmonary alveolar proteinosis presented with respiratory failure. WLL was planned. LUS was used to study the stages of lung flooding as previously described for ARDS model.6 areas screened based on six areas that are normally examined like upper zone, mid zone and lower zone showed alveolar interstitial pattern. One lung ventilation (OLV) was done and isolation of lavage lung was confirmed which was seen as lung collapse (lung pulse) on LUS. Saline infusion resulted in increase in B lines followed by tissue like pattern with fluid bronchogram on LUS(alveolar flooding) in all the areas. During the lavage of the second lung, appearance of alveolar flooding pattern resulted in termination of saline infusion. The use of LUS in monitoring WLL reduced amount of saline used for lavage, pick up complications like pleural effusion and spillage.
Background: Copper plays a definitive role in normal function and development of the body. Previous studies have shown that suboptimal copper intake during fetal development contributes to occurrence of birth defects in humans. Copper deficiency is more common in pregnancy especially in developing countries like India. Prevalence studies on copper levels in pregnant women in south Indian population are scanty and needs to be evaluated. Aim: The aim of this study is to assess serum copper levels during pregnancy and its association with dietary intake, socioeconomic status, gestational age and parity. Materials and methods: This cross sectional study included a total of 54 healthy pregnant women in the rural area of chengalpettu district, Tamil Nadu. A proforma was used to collect a detailed obstetric history and their average daily dietary intake in terms of copper was assessed by using a weekly standardized food frequency questionnaire. Serum Copper level was estimated using colorimetric method. Results: Serum copper levels were deficient in 3.7% of the study population with mean serum copper levels of 193.93±79.24 µg/dl in study population. The dietary intake of copper was found to be deficient <2 Cu (mg/day) in entire study population. There was statistically significant association between serum copper and maternal age, parity but no significant association between copper levels with respect to demographic characteristics. Conclusion: Dietary intake of copper needs to be increased by nutrition related counselling given to pregnant women. Larger studies are required to understand the magnitude of copper deficiency among pregnant women in India.
Ectopic pregnancy is a not uncommon condition, but instances of ectopic pregnancy in a rudimentary horn of a uterus are sufficiently rare to merit publication of a case-report.
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