The syndrome of Stevens-Johnson (SJS) and toxic epidermal necrolysis (TEN) are serious, mostly medicated, cutaneous adverse reactions, normally linked to a high degree of morbidity and mortality. Recently, the SJS/TEN management guidance, the Indian guidelines and the United Kingdom directives have been written in details. However, there is no agreement on SJS/TEN management. In this paper, we would like to conceptualise SJS/TEN system in order of Indian schedule. It has been found useful to discontinue all drugs early, take help steps (hydration, electrolytes, and skin care denuded), corticosteroids, and cyclosporine. Oral provocation tests are only available to those receiving full remission that are strictly attentive during hospitalisation. As there is no majority, care on an individual basis should be personalised.
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