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Background: Fetal biophysical profile is a well-established method of antepartum surveillance in high risk pregnancy. Classical biophysical profile with all parameters (fetal breathing movements, fetal tone, fetal gross body movements, amniotic fluid volume and non-stress test) needs two phase testing by ultrasound and external Doppler monitor to record fetal heart rate, is more cumbersome, time consuming and expensive.Methods: This study was a prospective clinical study which consisted of 70 patients having pregnancy with high risk factors. The patients were evaluated with the modified biophysical profile consisting of NST recording for 20mins, followed ultrasound assessment of amniotic fluid volume, using four quadrant technique.Results: When the Modified biophysical profile is normal, it gives reassurance that the fetal status is good with good perinatal outcome. When the MBPP is abnormal there is increased incidence of perinatal morbidity as well as mortality.Conclusions: Modified biophysical profile is an effective primary antepartum fetal surveillance test in high risk pregnancies in predicting perinatal outcome.

Background: Objectives of current study were to study the significance of Doppler in PIH using middle cerebral artery and umbilical artery blood flow and to analyze the role of Doppler in PIH in predicting perinatal outcome. Methods: Hundred cases of women with pregnancy induced hypertension between 28-40 weeks of gestation were studied for umbilical artery and middle cerebral artery Doppler waveforms. The perinatal outcome results were documented and analyzed statistically using percentage and Chi-square test. Results: Adverse perinatal outcome was significantly associated with oligohydramnios (P <0.0001) and grade 3 placental maturity (P <0.01). Absent end diastolic flow waveform in umbilical artery was associated with mortality of 27.78% and reverse end diastolic waveform with mortality of 100%. UA PI has the highest sensitivity (88.88%) and positive predictive value (69.56%) in predicting low birth weight. Cerebroplacental ratio (MCA/UA) had highest sensitivity (94.42%), PPV (86.42%), accuracy (90%) for predicting adverse perinatal outcome than UAPI and MCA PI. MCA PI had low specificity in predicting adverse perinatal outcome. Conclusions: Pregnancy induced hypertension is associated with significant fetal morbidity and mortality. Oligohydramnios in PIH patients is associated with adverse pregnancy outcome. Presence of absent end diastolic flow and reversed end diastolic flow in umbilical artery is an ominous sign with high perinatal mortality. Reversed end diastolic flow is more ominous than absent end diastolic flow. Cerebroplacental ratio (MCA/UA PI) is a better predictor of adverse perinatal outcome, with highest diagnostic accuracy, sensitivity, and positive predictive value, than either vessel Doppler indices considered alone. Colour Doppler study is a simple, quick, non-invasive procedure and is found to be the most accurate among the other tests for antepartum fetal surveillance.

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Aim: The present study was designed to correlate the serum and salivary glucose levels and estimate associated salivary parameters (such as salivary flow rate, pH and buffering capacity) among diabetic and healthy individuals. Settings and Design: 80 patients were included in this study of which 30 patients were uncontrolled diabetics (group I), 30 patients were controlled diabetics (group II) and 20 patients were healthy individuals (group III). Materials and Methods: Salivary and serum glucose levels and salivary flow rate were measured using established methods. Results: The mean serum glucose was higher in group I as compared to group II and group III. In all the groups, salivary glucose levels significantly correlated with serum glucose levels. A statistically significant correlation was also observed between salivary glucose and salivary flow rate in all the three groups. The mean pH values were similar in all the three groups, indicating unaltered salivary buffering capacities. Conclusion: Salivary glucose levels may be used as an alternative and reliable index in diagnosis of diabetes mellitus.