: Pyrexia is a one of the most common symptomatic presentations of disease. A lot of research is going on worldwide towards finding antipyretic agents from the natural sources. The main aim of the present study was to evaluate the antipyretic potential of petroleum ether, chloroform and methanol extracts (100 mg/kg, 200 mg/kg) of Pterospermum canescens, Roxb., (Sterculiaceae (leaves, stem and stem bark) was investigated for its antipyretic activity. Pyrexia was induced in Wistar Albino rats by Brewer's yeast (10mg/kg), were used in this study to assess anti-pyretic potential of the plant using Indomethacin as standard (10 µg/kg). Petroleum ether, chloroform and methanol extracts of leaf, stem and stem bark were exhibited (P < 0.001) anti-inflammatory activity at 100 mg/kg and 200 mg/kg doses when compared with the standard, while methanol stem (100mg/kg) extract exhibited significant activity (p <0.05).

Hugonia mystax L., (Linaceae), is commonly distributed in the thorny scrubs and tropical dry evergreen forests of Tamil Nadu, which has been valued for centuries in traditional system of medicine for the treatment of various ailments. In the present study was an attempt to investigate the phytochemical nature and anti-inflammatory, antimicrobial potential by adopting suitable methods. Phytochemical analysis of Hugonia mystax L., plant extracts revealed the presence of various biochemical compounds such as alkaloids, flavonoids, glycosides, triterpenoids and saponins etc. Since triterpenoids and flavonoids have remarkable anti-inflammatory activity, so our present work aims at evaluating in vitro anti inflammatory activity of Hugonia mystax L., by HRBC membrane stabilization method. The inhibition of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The percentage of membrane stabilization for ethanolic extracts and Diclofenac sodium were done at different concentrations. The maximum membrane stabilization of Hugonia mystax L., extracts was found to be 94.97 % at a dose of 2000 μg/ml. Therefore, our studies support the isolation and the use of active constituents from Hugonia mystax L., in treating inflammations.

Dalbergia spinosa Roxb. (Family: Leguminosae-Papilionoideae), a large climbing shrub commonly found in mangroves along the Coromandel coasts of south India. Root is bitter taste, used to treat inflammations, urinary problems, pain and fever and also reported for various pharmacological properties such as hypothermic, spermicidal, semen coagulant, hypoglycemic, cardio vascular, antimicrobial, diuretic and analgesic. In the present study, pharmacognostical investigation on roots was carried out by determining the morphological, micro scopical and physicochemical parameters. It was found that the root is cylindrical, elongated, tuberous in nature with lateral branches, yellowish brown in colour, slightly sweet taste with aromatic odour. Microscopical evaluation reveals that the presence of brown coloured cork cells and the periderm is distinguished into phellum, phellogen and phelloderm, made up of parenchyma followed by secondary phloem and xylem consists of vessels, fibres and lignified parenchyma. Histochemical studies of the root exhibits the presence of polyphenols, lignins and total proteins in the cortical cells, vessels and phloem respectively.

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Pain is an perception alone which does not require cortex. A lot of research is going on worldwide towards finding analgesic agents from the natural sources. The main aim of the present study was to investigate analgesic activity of petroleum ether, chloroform and methanol extracts (100 mg/kg, 200 mg/kg) of Pterospermum canescens, Roxb., (Sterculiaceae-leaf, stem and stem bark) andwas carried out by eddy's hot plate method using Indomethacin as standard (10 µg/kg). This present investigation revealsthat the methanol leaf and stem bark extracts were exhibited significant (P < 0.05) increase in animal reaction time to heat stimulus that at 200 mg/kg in experimental animals.