No abstract

Disturbances of B cell homeostasis may be critical in TA. Circulating plasmablasts could be a useful biomarker of disease activity and a tool for selecting appropriate candidates for BCDT. B cells and plasmablasts/plasma cells may therefore represent novel targets for effective therapies for TA.

Treatment with glucocorticoids failed. The patient's symptoms improved significantly after initiation of interferon-alpha therapy.

Figure 1 CT scan of the thorax showing marked pericardial effusion (arrow) and bilateral pleural effusions (left greater than right) (arrow): mediastinal windows.