A general method is described for the synthesis of 2‐amino‐3‐carbethoxy‐l‐hydroxyindoles by the reductive cyclization of 2‐nitrophenylcyanoacetates using zinc and acetic acid at temperatures of 15–28°.
Die Triphenylbutyrolactone (I) werden mit Diisobutylaluminiumhydrid (DIBAH) zu den Triphenylfuranen (II) reduziert, die mit den entsprechenden Chloriden (III) zu den Aminoäthyläthern (IV) reagieren.
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