Regioselectivity of the Reaction of Methallyl Isothiocyanate with Monosubstituted Hydrazines
Methallyl isothiocyanate 1 reacts with substituted aryl hydrazines to 1,4‐ respectively 2,4‐disubstituted thiosemicarbazides 4 and 5 in dependence on the reaction conditions and the nature of the aryl group. The influence of the substituents is discussed. The novel N′‐mono‐ and disubstituted N‐methallylic thioureas 2 and 3 are synthesized.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.