Thirty-five patients suffering from vulvo-vaginal candidosis were treated with econazole vaginal suppositories for 3 consecutive days, on a once-a-day schedule. In 80% of the cases clinical symptoms subsided and the mycological findings became negative. No side-effects were observed or reported, and the tolerability was excellent.
Pointing out the fact that there is a generalized increase in the incidence of vaginal candidiasis the authors describe a study involving a total of sixty-one patients to evaluate econazole in the treatment of the condition.
Diagnostic, therapeutic and prognostic aspects are interpreted on the basis of two cases of Echinococcus alveolaris. Both patients had undergone partial hepatectomy and were subsequently treated chemotherapeutically. In one case dehydroemetine and mebendazole (Vermox, Janssen), and in the other case metrifonate (Bilarcil, Bayer A.G.) were used. The diagnosis of alveococcosis of the liver was demonstrated in one case histologically on the occasion of appendectomy, and in the other case by the indirect immunofluorescence test and passive haemagglutination. In case of suspected alveococcosis these serological are imperative, as they are the most reliable methods of demonstrating this disease. The latest trend in theraphy aims at a combination of surgery and chemotherapy. Mebendazole seems to be promising as an anthelmintic agent for the treatment of alveococcosis. Remission of the disease was obtained in either case.
A clinical study was undertaken, in twenty-four patients with atrophic vaginal changes, to assess the efficacy and the acceptability of treatment with Ortho-Gynesi vaginal suppositories, which have as their active constituent the naturally occurring substance oestriol. A regenerative effect on the vaginal epithelium could be objectively demonstrated by an increase in the proportion of superficial cells following treatment. Changes in the vaginal epithelium were accompanied by a diminution in the incidence of infection and inflammation. Subjective complaints such as dyspareunia, pruritus and kraurosis vulvae, which could also be ascribed to a relative oestrogen deficiency, responded well to treatment.
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