The current study was investigated to explore the biogenic molecules of Sargassum wightii collected from the south east of Tamil Nadu, India. The biogenic molecules extracted from Sargassum wightii by using methanol as a solvent and the analysis was carried out by using UV-Visible spectroscopy and FT-IR. The UV-Visible spectrum of the methanolic extract of Sargassum wightii exposed the existence of the biogenic molecules separated from 200 -1100 nm among the absorption. The incidence of peaks from 234-676 nm discovered the presence of flavonoids and its derivatives. The unprocessed methanolic extract of Sargassum wightii was travelled in to FT-IR and it indicated the being of phenols and flavonoids their functional groups such as alcohol, alkane, carboxylic acids, esters, ethers, alkynes and aromatics. From the results, the future aim of this study is necessary to develop the target site to treat dreadful diseases.
Abstract:The amylase producing fungi were isolated from spoiled fruits, vegetables and soil, in and around Bangalore, Karnataka, India. The isolates were identified and five fungal species were screened. The best amylase producer among them, Aspergillus sp was selected for enzyme production by both sub merged fermentation using mineral salt medium (MSM) and solid state fermentations using wheat bran as a solid substrate. The various parameters influencing solid state fermentation were optimized. The most important factors are such as pH, incubation temperature, incubation period, carbon sources, nitrogen sources and moisture content. The maximum amount of enzyme production was obtained when solid state fermentation was carried out with soluble starch as carbon source and beef extract (1% each) as nitrogen source, optimum conditions of pH 7.0, an incubation temperature of 25 (±2) °C, incubation time 96 h and 62% moisture content.
Seaweeds are one of the most diverse bioreserves, including a wide range of bioactive compounds
with various properties and functions. In present study, the antioxidant and anticancer activity of
brown seaweed Turbinaria ornata was extracted using two different solvents like aqueous and ethanol.
Higher concentrations of bioactive compounds were observed in ethanolic extract of T. ornata (EETO)
in comparison to aqueous extract of T. ornata (AETO). The ethanolic extract showed potent antioxidant
properties for DPPH and hydroxyl radical scavenging. The IC50 value of the ethanolic extract was
found to be 48 and 50 μg/mL for DPPH and hydroxyl radical scavenging assay, respectively. Human
breast adenocarcinoma (MCF-7) cells treated with different concentrations of the ethanolic extract
showed a dose-dependent increase in cell inhibition. The LC50 value of the ethanolic extract was
calculated to be 115.19 μg/mL and cell morphology was observed under an inverted phase-contrast
microscope. As a result, based on the present findings, it is suggested that T. ornata extract might be a
promising antioxidant and anticancer therapeutics.
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