Summary 1. Electrical activities of the cerebral cortex and the brain stem, flexion reflex and the muscular tension of the hind limb of rats were recorded and the effect of Myanesin on them studied. 2. By administration of Myanesin, muscular tension was first suppressed, the electrical activities of the brain stem and the brain stem factor (peaks in 150 msec) of the flexion reflex were suppressed, and then the cortical activities and the cortical factor (peaks in 200msec. or more) of the flexion reflex curve were suppressed. 3. Recovery of the electrical activities and the flexion reflex preceded that of the muscular tension.
Summary 1. The flexion reflex curve was analyzed by a series of physiological methods, and the effect of some narcotics, electroshock and audiogenic seizure upon this reflex and also the development of flexion reflex in infant rats were studied. 2. The flexion reflex curve consists of three components, the preceeding peaks (30, 60–80 msec.) which originate from the spinal center, the intermediate ones (100–200 msec.) from the brain stem, and the delyayed ones (200 msec. and later) from the cerebral cortex. 3. It might be considered that the 1st group of narcotics (Dial, Chloralose, Evipan‐Na.) exhibits effect upon the cortical function, the 2nd group (Erovarin, Pentobarbital‐Na, Adalin, Luminal, Chlo‐ralhydrate, Chlorethyl) take effect upon the thalamic function, and the 3rd group (Urethan, Alcohol, Ether) effect on the spinal cord. 4. The latent period of the flexion reflex reads very long on the first day after birth, to get abruptly shorter one weak later. The record of the 25th day proves about the same latent period and the same form of flexion reflex curve as in the adult rat, 5. Within 10 seconds after the audiogenic seizure, the activity of brain stem and cerebral cortey gets abolished, the activity of the cerebral cortex starting to recover from I minute on. The activity of the spinal center is facilitated in no‐seizure state, but inhibited just before the seizure. 6. Within 15 seconds after electroshock, the activity of cerebral cortex and brain stem gets wholly abolished, this activity of cerebral cortex tends to begin to recover only gradually from 2 minutes on.
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