A granuloma annulare-like drug reaction is a rarely encountered clinical entity. A 64-year-old Caucasian female developed a granuloma annulare-like reaction 13 days after starting amlodipine and cleared within 3 months after drug cessation. The eruption consisted of multiple erythematous pruritic papules, distributed symmetrically over the lateral aspects of the legs and thighs, as well as on both palms. Histology showed focal collagen degeneration and significant interstitial histiocytic dermal infiltrate suggestive of granuloma annulare. We review previously reported cases of granuloma annulare-like drug reactions, in the context of a recently proposed classification for drug-induced interstitial granulomatous reactions.

These results suggest that there appears to be a good correlation between the degree of lateral order, shrinkage, crystallinity, and crease recovery angle on the one hand and the dimensional deformation on the other. Deformation and, subsequently, the dimensional stability of fibers can thus be assumed quickly by observing in the SEM the shapes and distortions of simple overhand knots prepared from the fibers under standard tensions. ACKNOWLEDGMENTSWe wish to thank Dr. T. Radhakrishnan, director, ATIRA, for permission to publish this work.

Some computed results of an energy method of analysis applied to single bar warp knitted structures (Part I) are presented. They are compared with experimental results and previous models of the warp knit structures in the literature. The single bar warp knit structures are characterized by a complex interlacing pattern and relatively little restriction to changes and redistribution of yam loop shape as the fabric is stretched. Computer results show that the yam loops are oriented to lie perpendicular to the fabric plane when the fabric is stretched. At the same time the fabric thickness is reduced. The distributed forces acting along the yams within a unit repeat of the single bar warp knitted structures are more peaked than those of the weft knitted fabrics. The forces of contact arising from the neighboring but not interlocking yarns within the repeat of the warp knit structure are significant. The single bar warp knit structures are compared to the weft knitted and woven fabrics by means of a redefined tightness parameter.