In a three year period, authors observed 16 cases whith plaque psoriasis accompanied with nail symptoms characteristic for typical psoriasis. Microscopy examinations were positive in cases of 7 in fingernails, and in 3 cases of toe nails. In cultures, pathogenic agents were grown in 4 cases from finger nails, in 2 cases from toe nails. Considering the 16 psoriasis cases out of the 1087 mycotic tests carried out in the 3 years period, onychomycosis occurred only in 1,5% of the cases. Therefore further studies are needed for the assessment of onychomycosis in psoriatic cases.
21and developed a mediastinitis bytlspergillus. All patients received lipid complexed amphotericin B (5 mg/Kg/die for 4 weeks).Results: Adults responded to antifungal therapy, the child died because of an ongoing infection in spite of therapy.
Conclusions:Clinical diagnosis is difficult due non-specific signs. Dialysis, superficial colonization and Aspergillus spores in the air should be taken in consideration for risk factors. Preventive treatments and full understanding of epidemiology is required. Prompt antifungal therapy could warrant to save patient's life.
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