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A 5-drug daily regimen with moxifloxacin results in significantly higher sputum culture conversion in the first 2 months compared with a thrice-weekly, 4-drug regimen in patients with newly diagnosed sputum-positive pulmonary tuberculosis.

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Microservice architecture style has been gaining wide impetus in the software engineering industry. Researchers and practitioners have adopted the microservices concepts into several application domains such as the internet of things, cloud computing, service computing, and healthcare. Applications developed in alignment with the microservices principles require an underlying platform with management capabilities to coordinate the different microservice units and ensure that the application functionalities are delivered to the user. A multitude of approaches has been proposed for the various tasks in microservices-based systems. However, since the field is relatively young, there is a need to organize the different research works. In this study, we present a comprehensive review of the research approaches directed toward microservice architectures and propose a multilevel taxonomy to categorize the existing research. The study also discusses the different distributed computing paradigms employing microservices and identifies the open research challenges in the domain.

Workflow is one of the important aspects of cloud computing today. Cloud computing is one of the fastest growing technologies in the world. Workflows can be used in cloud as we use them in grid. Many operations in the cloud are based on workflow execution. Workflow systems are now becoming more complex and for such kind of systems efficient workflow management is important. Workflow scheduling is an important part of workflow management. Scheduling in general is NP-hard problem. To solve such kind of problems exhaustive methods cannot be used. Only non-exhaustive techniques can be used. In this paper we have used a metaheuristic approach called bat algorithm. Bat algorithm is specifically designed for optimizing hard problems. Here, bat algorithm with the help of binary bat algorithm is used for scheduling workflow in a cloud. Specifically the mapping of tasks and resources is done using this method. The optimal resources are selected such that the overall cost of the workflow is minimal.

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The concept of virtualization forms the heart of systems like the Cloud and Grid. Efficiency of systems that employ virtualization greatly depends on the efficiency of the technique used to allocate the virtual machines to suitable hosts. The literature contains many evolutionary approaches to solve the virtual machine allocation problem, a broad category of which employ Genetic Algorithm. This paper proposes a novel technique to allocate virtual machines using the Family Gene approach. Experimental analysis proves that the proposed approach reduces energy consumption and the rate of migrations, and hence offers much scope for future research.