Background:The treatment of patients with partially atrophic rib and rib defects requires an ideal arc of the rib that has adequate bone length and width. To design and assemble a distraction device with a strain gauge, we need to establish an animal model for testing it during rib distraction osteogenesis.Methods:Osteotomies were performed at the same position in the fifth rib in 8 rabbits. Customized distraction devices attached to strain gauges were used to distract the ribs. After a month of distraction and consolidation, loading deflection gauges were used, and specimens were examined histologically to record bone formation.Results:Distraction osteogenesis was carried out successfully in all rabbits when the device used to distract the rib up to 4 cm.Conclusions:The device can be used for strain testing during rib distraction osteogenesis performed in a rabbit model. There was no significant difference in the loading deflection gauges of the bone between osteogenic and contralateral ribs. This animal model of costal distraction osteogenesis is successful.
Our study aimed to create a rabbit model of rib distraction osteogenesis, for use in treatment of rib defects and research on the process of distraction osteogenesis. Ten rabbits were subjected to unilateral osteotomy and a specific distractor was installed. The distractors were normally designed. Two rabbits died from anesthesia. Eight female rabbits underwent rib osteotomies, and lateral distraction devices were implanted. Three days postoperatively, distraction commenced on one side in each rabbit, by 0.5 mm twice a day for 80 days. Four rabbits each were sacrificed 15 and 30 days later, respectively, and the osteogenic and contralateral ribs were removed for histomorphometric examination. Normal development of distraction osteogenesis was observed, and the structure of newly formed bone was the same as that of other parts of the rib. Histomorphometric and gross tissue appearance of the areas subjected to distraction osteogenesis were the same as the other parts of the rib. We successfully established an animal model of rib distraction and documented the entire process of extension. Rib distraction was performed by 0.5 mm twice a day. Following a fixed period of 30 days, the biological characteristics of the distracted and contralateral normal rib showed no difference. Moreover, the distracted rib had curvature.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.