The BIM (Building Information Modeling) operation and maintenance management system of the nuclear power plant has been developed to cope with the security risks in the operation and maintenance process of nuclear power plant, the difficulty in querying the operation and maintenance status, the low work efficiency and the difficulty in statistical analysis of various large-scale operation and maintenance data. Practice has shown that the BIM operation and maintenance management system enhances the safety of the plant; on the other hand, the convenience of the results information query improves the professionalization, refinement and systematization of the nuclear power plant safety and operation management; in that way, the safety management efficiency of nuclear power plants will be comprehensively improved.