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[1] We analyzed neutral winds, ambipolar diffusion coefficients, and neutral temperatures observed by the Nippon/Norway Tromsø Meteor Radar (NTMR) and ion temperatures observed by the European Incoherent Scatter (EISCAT) UHF radar at Tromsø (69.6°N, 19.2°E), during a major stratospheric sudden warming (SSW) that occurred in January 2009. The zonal winds at 80-100 km height reversed approximately 10 days earlier than the zonal wind reversal in the stratosphere and the neutral temperature at 90 km decreased simultaneously with the zonal wind reversal at the same altitude. We found different variations between geomagnetically quiet nighttime ion temperatures at 101-110 km and 120-142 km for about 10 days around the SSW. Our results from the ground-based observations agree well with the satellite observations shown in an accompanying paper. Thus, this study indicates that a SSW is strongly linked to thermal structure and dynamics in the highlatitude mesosphere, lower thermosphere, and ionosphere.

The rotational temperature and number density of molecular nitrogen (N 2 ) in the lower thermosphere were measured by the N 2 temperature instrument onboard the S-310-35 sounding rocket, which was launched from Andøya at 0:33 UT on 13 December 2004, during the Dynamics and Energetics of the Lower Thermosphere in Aurora (DELTA) campaign. The rotational temperature measured at altitudes between 95 and 140 km, which is expected to be equal to neutral temperature, is much higher than neutral temperature from the Mass Spectrometer Incoherent Scatter (MSIS) model. Neutral temperatures in the lower thermosphere were observed using the auroral green line at 557.7 nm by two Fabry-Perot Interferometers (FPIs) at Skibotn and the Kiruna Esrange Optical Platform System site. The neutral temperatures derived from the look directions closest to the rocket correspond to the rotational temperature measured at an altitude of 120 km. In addition, a combination of the all-sky camera images at 557.7 nm observed at two stations, Kilpisjärvi and Muonio, suggests that the effective altitude of the auroral arcs at the time of the launch is about 120 km. The FPI temperature observations are consistent with the in situ rocket observations rather than the MSIS model.

The onset of oral candidiasis is accompanied by inflammatory symptoms such as pain in the tongue, edema or tissue damage and lowers the quality of life (QOL) of the patient. In a murine oral candidiasis model, the effects were studied of terpinen-4-ol (T-4-ol), one of the main constituents of tea tree oil, Melaleuca alternifolia, on inflammatory reactions. When immunosuppressed mice were orally infected with Candida albicans, their tongues showed inflammatory symptoms within 24 h after the infection, which was monitored by an increase of myeloperoxidase activity and macrophage inflammatory protein-2 in their tongue homogenates. Oral treatment with 50 µL of 40 mg/mL terpinen-4-ol 3h after the Candida infection clearly suppressed the increase of these inflammatory parameters. In vitro analysis of the effects of terpinen-4-ol on cytokine secretion of macrophages indicated that 800 µg/mL of this substance significantly inhibited the cytokine production of the macrophages cultured in the presence of heat-killed C. albicans cells. Based on these findings, the role of the anti-inflammatory action of T-4-ol in its therapeutic activity against oral candidiasis was discussed.

Abstract.Simultaneous observations were conducted with a Fabry-Perot Interferometer (FPI) at a wavelength of 557.7 nm, an all-sky camera at a wavelength of 557.7 nm, and the European Incoherent Scatter (EISCAT) UHF radar during the Dynamics and Energetics of the Lower Thermosphere in Aurora 2 (DELTA-2) campaign in January 2009. This paper concentrated on two events during periods of pulsating aurora. The lower-thermospheric wind velocity measured with the FPI showed obvious fluctuations in both vertical and horizontal components. Of particular interest is that the location of the fluctuations was found in a darker area that appeared within the pulsating aurora. During the same time period, the EISCAT radar observed sporadic enhancements in the F-region backscatter echo power, which suggests the presence of low-energy electron (1 keV or lower) precipitation coinciding with increase in amplitude of the electromagnetic wave (at the order of 10 Hz or higher). While we have not yet identified the dominant mechanism causing the fluctuations in FPI-derived wind velocity during the pulsating aurora, the frictional heating energy dissipated by the electric-field perturbations may be responsible for the increase in ionospheric thermal energy thus modifying the local wind dynamics in the lower thermosphere.

[1] To study the spatial structure of midlatitude sporadic E (E s ) layers, the ultraviolet resonant scattering by magnesium ions (Mg + ) in an E s layer was observed during the evening twilight with the Magnesium Ion Imager (MII) on the sounding rocket launched from the Uchinoura Space Center in Kagoshima, Japan. The in situ electron density measured by an onboard impedance probe showed that the E s layer was located at an altitude of 100 km during both the ascent and descent of the flight. Simultaneous observation with a ground-based ionosonde at Yamagawa identified the signature of horizontally "patchy" structures in the E s layer. The MII successfully scanned the horizontal Mg + density perturbations in the E s layer and found that they had patchy and frontal structures. The horizontal scale and alignment of the observed frontal structure is generally consistent with a proposed theory. To our knowledge, this is the first observation of the two-dimensional horizontal structure of Mg + in an E s layer.Citation: Kurihara, J., et al. (2010), Horizontal structure of sporadic E layer observed with a rocket-borne magnesium ion imager,

High-latitude ionospheric variations at times near auroral substorms exhibit large temporal variations in both vertical and horizontal extents. Statistical analysis was made of data from the European Incoherent Scatter UHF radar at Tromsø, Norway, and International Monitor for Auroral Geomagnetic Effects magnetometer for finding common features in electron density, ion and electron temperatures and relating these to currents and associated heating. This paper particularly focused on the height dependencies. Results show clear evidences of large electric field with corresponding frictional heating and Pedersen currents located just outside the front of the poleward expanding aurora, which typically appeared at the eastside of westward traveling surge. At the beginning of the substorm recovery phase, the ionospheric density had a large peak in the E region and a smaller peak in the F region. This structure was named as C form in this paper based on its shape in the altitude-time plot. The lower altitude density maximum is associated with hard auroral electron precipitation probably during pulsating aurora. We attribute the upper F region density maximum to local ionization by lower energy particle precipitation and/or long-lived plasma that is convected horizontally into the overhead measurement volume from the dayside hemisphere.

[1] A coordinated observation of the atmospheric response to auroral energy input in the polar lower thermosphere was conducted during the Dynamics and Energetics of the Lower Thermosphere in Aurora (DELTA) campaign. N 2 rotational temperature was measured with a rocket-borne instrument launched from the Andøya Rocket Range, neutral winds were measured from auroral emissions at 557.7 nm with a Fabry-Perot Interferometer (FPI) at Skibotn and the KEOPS, and ionospheric parameters were measured with the European Incoherent Scatter (EISCAT) UHF radar at Tromsø. Altitude profiles of the passive energy deposition rate and the particle heating rate were estimated using data taken with the EISCAT radar. The local temperature enhancement derived from the difference between the observed N 2 rotational temperature and the MSISE-90 model neutral temperature were 70-140 K at 110-140 km altitude. The temperature increase rate derived from the estimated heating rates, however, cannot account for the temperature enhancement below 120 km, even considering the contribution of the neutral density to the estimated heating rate. The observed upward winds up to 40 m s À1 seem to respond nearly instantaneously to changes in the heating rates. Although the wind speeds cannot be explained by the estimated heating rate and the thermal expansion hypothesis, the present study suggests that the generation mechanism of the large vertical winds must be responsible for the fast response of the vertical wind to the heating event.