A novel chiral 1,5‐N,N‐bidentate ligand based on a spirocyclic pyrrolidine oxazoline backbone was designed and prepared, and it coordinates CuBr in situ to form an unprecedented catalyst that enables efficient oxidative cross‐coupling of 2‐naphthols. Air serves as an external oxidant and generates a series of C1‐symmetric chiral BINOL derivatives with high enantioselectivity (up to 99 % ee) and good yield (up to 87 %). This approach is tolerant of a broader substrates scope, particularly substrates bearing various 3‐ and 3′‐substituents. A preliminary investigation using one of the obtained C1‐symmetric BINOL products was used as an organocatalyst, exhibiting better enantioselectivity than the previously reported organocatalyst, for the asymmetric α‐alkylation of amino esters.
Aeolian processes have been studied extensively at low elevations, but have been relatively little studied at high elevations. Aeolian sediments are widely distributed in the Yarlung Zangbo River basin, southern Tibetan Plateau, which is characterized by low pressure and low temperature. Here, we comprehensively analyzed the wind regime using data since 1980 from 11 meteorological stations in the study area, and examined the interaction between the near-surface wind and aeolian environment. The wind environment exhibited significant spatial and temporal variation, and mean wind speed has generally decreased on both annual and seasonal bases since 1980, at an average of 0.181 m/(s•10a). This decrease resulted from the reduced contribution of maximum wind speed, and depended strongly on variations of the frequency of sand-driving winds. The drift potential and related parameters also showed obvious spatial and temporal variation, with similar driving forces for the wind environment. The strength of the wind regime affected the formation and development of the aeolian geomorphological pattern, but with variation caused by local topography and sediment sources. The drift potential and resultant drift direction were two key parameters, as they quantify the dynamic conditions and depositional orientation of the aeolian sediments. Wind affected the spatial variation in sediment grain size, but the source material and complex topographic effects on the near-surface wind were the underlying causes for the grain size distribution of aeolian sands. These results will support efforts to control aeolian desertification in the basin and improve our understanding of aeolian processes in high-elevation environments.
A facile and environmentally benign KI(cat.)/NaBO3·4H2O oxidation system has been developed for the tandem oxidative aminocyclization/coupling of tryptamines, affording a series of 3a,3a′-bispyrrolidino[2,3-b]indolines with high efficiency (up to 94% yield).
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