Our preliminary results demonstrate the feasibility of the CNN-based approach, and this scheme outperforms the NMC- and LREG-based methods. Advances in knowledge: This method reduces the registration time from ~1 h to ~1 min, which has promising prospects for clinical use. To the best of our knowledge, this study shows the first convolutional neural network-based registration method to be applied in abdominal images.

In this study, we proposed a model combing parallel imaging (PI) with generative adversarial network (GAN) architecture (PIC-GAN) for accelerated multi-channel magnetic resonance imaging (MRI) reconstruction. This model integrated data fidelity and regularization terms into the generator to benefit from multi-coils information and provide an “end-to-end” reconstruction. Besides, to better preserve image details during reconstruction, we combined the adversarial loss with pixel-wise loss in both image and frequency domains. The proposed PIC-GAN framework was evaluated on abdominal and knee MRI images using 2, 4 and 6-fold accelerations with different undersampling patterns. The performance of the PIC-GAN was compared to the sparsity-based parallel imaging (L1-ESPIRiT), the variational network (VN), and conventional GAN with single-channel images as input (zero-filled (ZF)-GAN). Experimental results show that our PIC-GAN can effectively reconstruct multi-channel MR images at a low noise level and improved structure similarity of the reconstructed images. PIC-GAN has yielded the lowest Normalized Mean Square Error (in ×10−5) (PIC-GAN: 0.58 ± 0.37, ZF-GAN: 1.93 ± 1.41, VN: 1.87 ± 1.28, L1-ESPIRiT: 2.49 ± 1.04 for abdominal MRI data and PIC-GAN: 0.80 ± 0.26, ZF-GAN: 0.93 ± 0.29, VN:1.18 ± 0.31, L1-ESPIRiT: 1.28 ± 0.24 for knee MRI data) and the highest Peak Signal to Noise Ratio (PIC-GAN: 34.43 ± 1.92, ZF-GAN: 31.45 ± 4.0, VN: 29.26 ± 2.98, L1-ESPIRiT: 25.40 ± 1.88 for abdominal MRI data and PIC-GAN: 34.10 ± 1.09, ZF-GAN: 31.47 ± 1.05, VN: 30.01 ± 1.01, L1-ESPIRiT: 28.01 ± 0.98 for knee MRI data) compared to ZF-GAN, VN and L1-ESPIRiT with an under-sampling factor of 6. The proposed PIC-GAN framework has shown superior reconstruction performance in terms of reducing aliasing artifacts and restoring tissue structures as compared to other conventional and state-of-the-art reconstruction methods.

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The preliminary results demonstrate the feasibility of the proposed SCAE-based strategy for correcting the streaking artifacts of undersampled free-breathing 3D abdominal MRI with a negligible reconstruction time.

BackgroundFunctional brain networks of human have been revealed to have small-world properties by both analyzing electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) time series.Methods & ResultsIn our study, by using graph theoretical analysis, we attempted to investigate the changes of paralimbic-limbic cortex between wake and sleep states. Ten healthy young people were recruited to our experiment. Data from 2 subjects were excluded for the reason that they had not fallen asleep during the experiment. For each subject, blood oxygen level dependency (BOLD) images were acquired to analyze brain network, and peripheral pulse signals were obtained continuously to identify if the subject was in sleep periods. Results of fMRI showed that brain networks exhibited stronger small-world characteristics during sleep state as compared to wake state, which was in consistent with previous studies using EEG synchronization. Moreover, we observed that compared with wake state, paralimbic-limbic cortex had less connectivity with neocortical system and centrencephalic structure in sleep.ConclusionsIn conclusion, this is the first study, to our knowledge, has observed that small-world properties of brain functional networks altered when human sleeps without EEG synchronization. Moreover, we speculate that paralimbic-limbic cortex organization owns an efficient defense mechanism responsible for suppressing the external environment interference when humans sleep, which is consistent with the hypothesis that the paralimbic-limbic cortex may be functionally disconnected from brain regions which directly mediate their interactions with the external environment. Our findings also provide a reasonable explanation why stable sleep exhibits homeostasis which is far less susceptible to outside world.

At present, with the advance of satellite image processing technology, remote sensing images are becoming more widely used in real scenes. However, due to the limitations of current remote sensing imaging technology and the influence of the external environment, the resolution of remote sensing images often struggles to meet application requirements. In order to obtain high-resolution remote sensing images, image super-resolution methods are gradually being applied to the recovery and reconstruction of remote sensing images. The use of image super-resolution methods can overcome the current limitations of remote sensing image acquisition systems and acquisition environments, solving the problems of poor-quality remote sensing images, blurred regions of interest, and the requirement for high-efficiency image reconstruction, a research topic that is of significant relevance to image processing. In recent years, there has been tremendous progress made in image super-resolution methods, driven by the continuous development of deep learning algorithms. In this paper, we provide a comprehensive overview and analysis of deep-learning-based image super-resolution methods. Specifically, we first introduce the research background and details of image super-resolution techniques. Second, we present some important works on remote sensing image super-resolution, such as training and testing datasets, image quality and model performance evaluation methods, model design principles, related applications, etc. Finally, we point out some existing problems and future directions in the field of remote sensing image super-resolution.

Medical image-to-image translation is considered a new direction with many potential applications in the medical field. The medical image-to-image translation is dominated by two models, including supervised Pix2Pix and unsupervised cyclic-consistency generative adversarial network (GAN). However, existing methods still have two shortcomings: 1) the Pix2Pix requires paired and pixel-aligned images, which are difficult to acquire. Nevertheless, the optimum output of the cycle-consistency model may not be unique. 2) They are still deficient in capturing the global features and modeling long-distance interactions, which are critical for regions with complex anatomical structures. We propose a Swin Transformer-based GAN for Multi-Modal Medical Image Translation, named MMTrans. Specifically, MMTrans consists of a generator, a registration network, and a discriminator. The Swin Transformer-based generator enables to generate images with the same content as source modality images and similar style information of target modality images. The encoder part of the registration network, based on Swin Transformer, is utilized to predict deformable vector fields. The convolution-based discriminator determines whether the target modality images are similar to the generator or from the real images. Extensive experiments conducted using the public dataset and clinical datasets showed that our network outperformed other advanced medical image translation methods in both aligned and unpaired datasets and has great potential to be applied in clinical applications.

CPAP therapy had a significant influence on sleep EEG in patients with OSAHS, which lead to a more stable EEG pattern. This may be one of the mechanisms that CPAP could improve sleep quality and brain function of OSAS patients.