ObjectiveEsophagogastroduodenoscopy (EGD) is the pivotal procedure in the diagnosis of upper gastrointestinal lesions. However, there are significant variations in EGD performance among endoscopists, impairing the discovery rate of gastric cancers and precursor lesions. The aim of this study was to construct a real-time quality improving system, WISENSE, to monitor blind spots, time the procedure and automatically generate photodocumentation during EGD and thus raise the quality of everyday endoscopy.DesignWISENSE system was developed using the methods of deep convolutional neural networks and deep reinforcement learning. Patients referred because of health examination, symptoms, surveillance were recruited from Renmin hospital of Wuhan University. Enrolled patients were randomly assigned to groups that underwent EGD with or without the assistance of WISENSE. The primary end point was to ascertain if there was a difference in the rate of blind spots between WISENSE-assisted group and the control group.ResultsWISENSE monitored blind spots with an accuracy of 90.40% in real EGD videos. A total of 324 patients were recruited and randomised. 153 and 150 patients were analysed in the WISENSE and control group, respectively. Blind spot rate was lower in WISENSE group compared with the control (5.86% vs 22.46%, p<0.001), and the mean difference was −15.39% (95% CI −19.23 to −11.54). There was no significant adverse event.ConclusionsWISENSE significantly reduced blind spot rate of EGD procedure and could be used to improve the quality of everyday endoscopy.Trial registration numberChiCTR1800014809; Results.

Partial substitution of Fe for Ni alone or both for Ni and Mn in the 5 V spinel cathode LiMn1.5Ni0.5O4 has been investigated by characterizing the samples by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), charge−discharge measurements in lithium cells, electrochemical impedance spectroscopy (EIS), chronoamperometry (CA), and X-ray photoelectron spectroscopy (XPS). The Fe-substituted samples exhibit remarkably superior cycling performances and higher rate capabilities than the pristine LiMn1.5Ni0.5O4. The greatly enhanced electrochemical performances by the Fe substitution are attributed to the (i) stabilization of the structure with cation-disorder in the 16d octahedral sites of the spinel lattice, (ii) suppression of the formation of a thick solid-electrolyte interfacial (SEI) layer due to the Fe-enrichment and Ni-deficiency on the surface, (iii) production of Mn3+ and the consequent enhancement in electronic conductivity, and (iv) much reduced polarization loss arising from both fast charge transfer kinetics and lithium ion diffusion kinetics in the bulk.

Glassy ferromagnetism is observed in diluted magnetic semiconductor Al-doped 4H-SiC. We propose a possible explanation for the origin of ferromagnetism order that is the coeffect of sp(2)/sp(3) configuration along with the structural defects. This result unambiguously demonstrates the existence of intrinsic ferromagnetism order in nonmagnetic sp systems.