The bioconcentration factors (BCF) for 15 pesticides by a freshwater fish (topmouth gudgeon) were measured under continuous flow conditions in water containing 5 to 20 μg litre−1 of each pesticide at the equilibrium condition. A significant correlation was found between the BCF by the fish and the water solubility of the pesticide or its partition coefficient (PC) between octan‐1‐01 and water. Moreover, a significant correlation was also found between the BCF by topmouth gudgeon and the acute toxicities to carp, rainbow trout and water flea. It would therefore appear that the bioconcentration potential of a pesticide by a fish may be predicted from knowledge of its solubility or PC, and that the acute toxicity of a pesticide to a fish may be predicted from knowledge of the BCF.
Our study supports the concept that the CDHR3 variant is an important susceptibility factor for severe adult asthma in individuals who develop the disease in early life. The interaction between the CDHR3 variant and atopy indicates that genetic predisposition to early respiratory viral infection is combined with atopy in promoting asthma.
Soil sorption constants based on the organic carbon content (Koc) of 15 pesticides were measured using two soils at three concentrations. Significant correlations were found between the Koc value and water solubility (WS), octanol/water partition coefficient (Kow), retention time in reversed‐phase HPLC (Rt) and molecular weight (mol. wt.). Thus the soil sorption constants of nonionic pesticides can be predicted by these four parameters.
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