In the production of novel biological products, plasmids are often engineered into delivery vectors for target genes, which can be used directly as vaccines or as intermediate products for gene/cell therapy. Plasmid DNA exists in several topological forms such as supercoiled, linear, and open circular. As supercoiled Abbreviations: AGE, agarose gel electrophoresis; dsDNA, double-stranded DNA; EDTA, ethylenediaminetetraacetic acid; IEX, ion exchange chromatography.
Temperature‐dependent dual fluorescence and switchable circularly polarized luminescence (CPL) are two highly pursued but challenging properties for small organic molecules (SOMs). We herein disclose a triarylborane π‐system based on a 2,2′‐diamino‐6,6′‐diboryl‐1,1′‐binaphthyl scaffold that can serve as a versatile building block for achieving these two properties by simply choosing different amino groups. BNMe2‐BNaph with less bulky dimethylamino groups displays temperature‐dependent dual fluorescence, and can thus be used as a highly sensitive ratiometric fluorescence thermometer. On the other hand, BNPh2‐BNaph with bulky diphenylamino groups exhibits intense fluorescence in both solution and in the solid state. A change of solvent from nonpolar cyclohexane to highly polar MeCN not only shifts the CPL position to much longer wavelength but also inverts the CPL sign. In addition, the complexation of BNPh2‐BNaph with fluoride greatly enhances the CPL intensity.
Photochemistry. In their Communication on page 4840 ff., Q. Peng, C.‐H. Zhao et al. describe the generation of a versatile building block for organic fluorophores with temperature‐dependent dual fluorescence and switchable circularly polarized luminescence.
Photochemie. In der Zuschrift auf S. 4894 beschreiben Q. Peng, C.‐H. Zhao et al. die Synthese eines vielseitigen Bausteins für organische Fluorophore mit temperaturabhängiger dualer Fluoreszenz und schaltbarer zirkular polarisierter Lumineszenz.
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