This study demonstrated comparable technical and clinical success rates between EUS-BD and ERCP in relief malignant distal biliary obstruction. Substantially longer duration of patency coupled with lower rates of adverse events and reintervention, and more preserved QOL were observed with EUS-BD (cris.nih.go.kr, Identifier: KCT0001396, https://cris.nih.go.kr/cris/search/search_result_st01_en.jsp?seq=9716<ype=&rtype= ).
EUS-BD and PTBD had similar levels of efficacy in patients with unresectable malignant distal biliary obstruction and inaccessible papilla based on rates of technical and functional success and QOL. However, EUS-BD produced fewer procedure-related adverse events and unscheduled re-interventions. Clinical trial registration no: cris.nih.go.kr/KCT0001370.
EUS-GBD with an SEMS for acute cholecystitis showed excellent long-term outcomes and may be a definitive treatment in patients who are unsuitable for cholecystectomy because of advanced malignancy or high surgical risk.
New limits are presented on the cross section for weakly interacting massive particle (WIMP) nucleon scattering in the KIMS CsI(Tℓ) detector array at the Yangyang Underground Laboratory. The exposure used for these results is 24 524.3 kg·days. Nuclei recoiling from WIMP interactions are identified by a pulse shape discrimination method. A low energy background due to alpha emitters on the crystal surfaces is identified and taken into account in the analysis. The detected numbers of nuclear recoils are consistent with zero and 90% confidence level upper limits on the WIMP interaction rates are set for electron equivalent energies from 3 to 11 keV. The 90% upper limit of the nuclear recoil event rate for 3.6-5.8 keV corresponding to 2-4 keV in NaI(Tℓ) is 0.0098 counts/kg/keV/day, which is below the annual modulation amplitude reported by DAMA. This is incompatible with interpretations that enhance the modulation amplitude such as inelastic dark matter models. We establish the most stringent cross section limits on spin-dependent WIMP-proton elastic scattering for the WIMP masses greater than 20 GeV/c2.
The standard model (SM) production of four top quarks (tt tt) in proton-proton collisions is studied by the CMS Collaboration. The data sample, collected during the 2016-2018 data taking of the LHC, corresponds to an integrated luminosity of 137 fb −1 at a center-of-mass energy of 13 TeV. The events are required to contain two same-sign charged leptons (electrons or muons) or at least three leptons, and jets. The observed and expected significances for the tt tt signal are respectively 2.6 and 2.7 standard deviations, and the tt tt cross section is measured to be 12.6 +5.8 −5.2 fb. The results are used to constrain the Yukawa coupling of the top quark to the Higgs boson, y t , yielding a limit of |y t /y SM t | < 1.7 at 95% confidence level, where y SM t is the SM value of y t. They are also used to constrain the oblique parameter of the Higgs boson in an effective field theory framework,Ĥ < 0.12. Limits are set on the production of a heavy scalar or pseudoscalar boson in Type-II two-Higgs-doublet and simplified dark matter models, with exclusion limits reaching 350-470 GeV and 350-550 GeV for scalar and pseudoscalar bosons, respectively. Upper bounds are also set on couplings of the top quark to new light particles.
The research looks at the structure of the Internet backbone and air transport networks between 82 cities in 2002, using Internet backbone bandwidth and air passenger traffic data. Centrality measures on individual city's hierarchy in the Internet and in the air traffic networks were significantly correlated, with London in the most dominant position in both networks. A quadratic assignment procedure (QAP) showed a structural equivalence between two systems. The division and membership of the clusters in both networks also showed similarity; both networks had a strongly cohesive North American‐European cluster with the London‐New York dyad as the strongest linkage in the global flow of information and people. These findings suggest that current trends in Internet infrastructure concentration reproduce and maintain global inequality and hierarchy among world cities.
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