ObjectivesTo evaluate the C-reactive protein serum levels in patients with pulmonary and
abdominal sepsis during the first five days of sepsis progression. Methods The present investigation was a retrospective cohort study conducted at the
university hospital with 345 patients who were admitted to the intensive care unit
and diagnosed with sepsis of pulmonary or abdominal origin. Serum C-reactive
protein concentrations were measured by the turbidimetric immunoassay. For
analysis of C-reactive protein, day 1 was defined as the day on which the patient
was clinically diagnosed with sepsis. Results Thirty-four patients with sepsis (9.8%), 114 patients with severe sepsis (33.0%),
and 197 patients with septic shock (57.2%) were evaluated. The age of the patients
was 56.4±19.8 years. The serum C-reactive protein concentrations were higher on
the day of sepsis diagnosis in the group with abdominal infection compared with
the group with pulmonary sepsis (17.8±10.1 mg/dL versus 14.9±11.1 mg/dL, p=0.025)
and remained significantly higher during the first five days of sepsis
progression. Conclusion The serum C-reactive protein concentrations were significantly higher in the
patients with abdominal sepsis compared with the patients with pulmonary sepsis
during the first five days of sepsis progression.
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