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Measures in Category I are strongly supported by well-designed and controlled clinical studies that show their effectiveness in reducing the risk of nosocomial infections or are viewed as effective by a majority of expert reviewers. Measures in this category are viewed as applicable for most hospitalsregardless of size, patient population, or endemic nosocomial infection rates. CATEGORY II Measures in Category II are supported by highly suggestive clinical studies in general hospitals or by definitive studies in specialty hospitals that might not be representative of general hospitals. Measures that have not been adequately studied but have a logical or strong theoretical rationale indicating probable effectiveness are included in this category. Category II recommendations are viewed as practical to implement in most hospitals. CATEGORY III Measures in Category III have been proposed by some investigators, authorities, or organizations, but, to date, lack supporting data, a strong theoretical rationale, or an indication that the benefits expected from them are cost effective. Thus, they are considered important issues to be studied. They might be considered by some hospitals for implementation, especially if the hospitals have specific nosocomial infection problems, but they are not generally recommended for widespread adoption.

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