One challenge of teaching chemical
analysis is the proliferation
of sophisticated, but often impenetrable, instrumentation in the modern
laboratory. Complex instruments, and the software that runs them, distance students from
the physical and chemical processes that generate the analytical signal.
A solution to this challenge is the introduction of a student-driven
instrument-building project. Visible absorbance spectroscopy is well-suited
to such a project due to its relative simplicity and the ubiquity
of absorbance measurements. This Article reviews simple instructor-
and student-built instruments for spectroscopy, providing an overview
of common designs, components, and applications. This comprehensive
summary includes options that are suitable for in-person or remote
learning with K–12 students and undergraduates in general chemistry,
analytical chemistry, instrumental analysis, and electronics courses.
The high surface area-to-volume ratio of microfluidic channels makes them susceptible to fouling and clogging when used for biological analyses,including cell-based assays. We evaluated the role of electrostatic and van...
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