We report the first electrochemical strategy to synthesize functionalizedn aphthalene derivatives through [4+ +2] annulation-rearrangement-aromatization from styrenes under mild conditions.T he electrolysis does not require metals,o xidants and high valence substrates,i ndicating the atom and step-economy ideals.T he dehydrodimer produced through [4+ +2] cycloaddition of 4-methoxy a-methyl styrene is isolated and proved to be the key intermediate for the following oxydehydrogenation to form carbon cation, whichu ndergoes rearrangement-aromatization to affordthe final products.This reaction represents ap owerful access to construct multisubstituted naphthalene blocks in as ingle step.
We report the first electrochemical strategy to synthesize functionalizedn aphthalene derivatives through [4+ +2] annulation-rearrangement-aromatization from styrenes under mild conditions.T he electrolysis does not require metals,o xidants and high valence substrates,i ndicating the atom and step-economy ideals.T he dehydrodimer produced through [4+ +2] cycloaddition of 4-methoxy a-methyl styrene is isolated and proved to be the key intermediate for the following oxydehydrogenation to form carbon cation, whichu ndergoes rearrangement-aromatization to affordthe final products.This reaction represents ap owerful access to construct multisubstituted naphthalene blocks in as ingle step.
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