Patients diseased with gynecological malignancies were believed untreatable with poor survival chances till hyperthermic intraperitoneal chemotherapy after capital cytoreductive surgery came into existence. Perioperative management of this patient, for a major surgery like CRS/HIPEC is complex and challenging. Major perioperative concerns in these patients include anesthetic challenges intraoperative fluid management, maintaining mean arterial blood pressure, thermoregulation electrolyte imbalances, significant blood loss and fluid shifts and renal toxicity after chemotherapeutic drugs administration. We report a case of 66 year old female diagnosed with carcinoma ovary with moderate ascites posted for cytoreductive surgery and HIPEC.
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