Currently, Coronavirus disease (COVID-19), one of the most infectious diseases in the 21st century, is diagnosed using RT-PCR testing, CT scans and/or Chest X-Ray (CXR) images. CT (Computed Tomography) scanners and RT-PCR testing are not available in most medical centers and hence in many cases CXR images become the most time/cost effective tool for assisting clinicians in making decisions. Deep learning neural networks have a great potential for building COVID-19 triage systems and detecting COVID-19 patients, especially patients with low severity. Unfortunately, current databases do not allow building such systems as they are highly heterogeneous and biased towards severe cases. This article is threefold: (i) we demystify the high sensitivities achieved by most recent COVID-19 classification models, (ii) under a close collaboration with Hospital Universitario Clínico San Cecilio, Granada, Spain, we built COVIDGR-1.0, a homogeneous and balanced database that includes all levels Manuscript

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Neurologic impairment persisting months after acute severe SARS-CoV-2 infection has been described because of several pathogenic mechanisms, including persistent systemic inflammation. The objective of this study is to analyze the selective involvement of the different cognitive domains and the existence of related biomarkers. Cross-sectional multicentric study of patients who survived severe infection with SARS-CoV-2 consecutively recruited between 90 and 120 days after hospital discharge. All patients underwent an exhaustive study of cognitive functions as well as plasma determination of pro-inflammatory, neurotrophic factors and light-chain neurofilaments. A principal component analysis extracted the main independent characteristics of the syndrome. 152 patients were recruited. The results of our study preferential involvement of episodic and working memory, executive functions, and attention and relatively less affectation of other cortical functions. In addition, anxiety and depression pictures are constant in our cohort. Several plasma chemokines concentrations were elevated compared with both, a non-SARS-Cov2 infected cohort of neurological outpatients or a control healthy general population. Severe Covid-19 patients can develop an amnesic and dysexecutive syndrome with neuropsychiatric manifestations. We do not know if the deficits detected can persist in the long term and if this can trigger or accelerate the onset of neurodegenerative diseases.

In this study, we analyze “Discrimination”, ”Bias”, “Fairness”, and “Trustworthiness” as working variables in the context of the social impact of AI. It has been identified that there exists a set of specialized variables, such as security, privacy, responsibility, etc., that are used to operationalize the principles in the Principled AI International Framework. These variables are defined in such a way that they contribute to others of more general scope, for example, the ones studied in this study, in what appears to be a generalization–specialization relationship. Our aim in this study is to comprehend how we can use available notions of bias, discrimination, fairness, and other related variables that will be assured during the software project’s lifecycle (security, privacy, responsibility, etc.) when developing trustworthy algorithmic decision-making systems (ADMS). Bias, discrimination, and fairness are mainly approached with an operational interest by the Principled AI International Framework, so we included sources from outside the framework to complement (from a conceptual standpoint) their study and their relationship with each other.

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Currently, Coronavirus disease (COVID-19), one of the most infectious diseases in the 21st century, is diagnosed using RT-PCR testing, CT scans and/or Chest X-Ray (CXR) images. CT (Computed Tomography) scanners and RT-PCR testing are not available in most medical centers and hence in many cases CXR images become the most time/cost effective tool for assisting clinicians in making decisions. Deep learning neural networks have a great potential for building triage systems for detecting COVID-19 patients, especially patients with low severity. Unfortunately, current databases do not allow building such systems as they are highly heterogeneous and biased towards severe cases. This paper is three-fold: (i) we demystify the high sensitivities achieved by most recent COVID-19 classification models, (ii) under a close collaboration with Hospital Universitario Clnico San Cecilio, Granada, Spain, we built COVIDGR-1.0, a homogeneous and balanced database that includes all levels of severity, from Normal with positive RT-PCR, Mild, Moderate to Severe. COVIDGR-1.0 contains 377 positive and 377 negative PA (PosteroAnterior) CXR views and (iii) we propose COVID Smart Data based Network (COVID-SDNet) methodology for improving the generalization capacity of COVID-classification models. Our approach reaches good and stable results with an accuracy of 97.37% ± 1.86%, 88.14%±2.02%, 66.5%±8.04% in severe, moderate and mild COVID severity levels. Our approach could help in the early detection of COVID-19. COVIDGR-1.0 dataset will be made available after the review process.

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In this article we propose an approach to the study of art history based on geography of Hispanic Baroque art by digital means that showcase the multiplicity of possible places of art. Our study advances four elements of a digital geography of art (communities, semantic maps, areas, and flows)-a methodology that can be expanded in future Digital Humanities research.